Results 151 to 160 of about 1,597,404 (298)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Transect-rapport 2959: Een Archeologisch Inventariserend Veldonderzoek door middel van Proefsleuven (IVO-P), karterende en waarderende fase. Sint Willebrord, Clausstraat 20. Gemeente Rucphen (NB).

In juli 2020 is een archeologisch inventariserend proefsleuvenonderzoek (IVO-P), karterende en waarderende fase uitgevoerd in een plangebied aan de Clausstraat 20 in Sint Willebrord (gemeente Rucphen).
Rendering, B.J.
core   +1 more source

Robust Local Cluster Neural Networks (ESANN) [PDF]

, 2006
Eickhoff R, Sitte J, Rückert U. Robust Local Cluster Neural Networks (ESANN). In: Proceedings of the 14th European Symposium on Artificial Neural Networks (ESANN).
Eickhoff, Ralf, Rueckert, Ulrich, Sitte, Joaquin, Rückert, Ulrich   +3 more
core  

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Transect-rapport 2905: Een Archeologisch Inventariserend Veldonderzoek door middel van Proefsleuven (IVO-P), karterende en waarderende fase. Leidschendam, Parnashofweg 29-29a, Gemeente Leidschendam-Voorburg (ZH).

In juli 2020 is een archeologisch inventariserend proefsleuvenonderzoek (IVO-P), karterende en waarderende fase uitgevoerd, in het plangebied aan de Parnashofweg 29-29a in Leidschendam (gemeente Leidschendam-Voorburg).
Rendering, B.J.
core   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Neural Rendering Techniques for Volume Visualization [PDF]

Volume rendering transforms raw scientific data into insightful images. It is an integral part of scientific visualization and crucial for analyzing complex data in physics, astronomy, biology, and medicine.
Bauer, David
core   +1 more source

Transect-rapport 2766: Een inventariserend veldonderzoek, Heusden - Catharinakerk

In opdracht van Peters Projectontwikkeling heeft Transect in april 2020 een archeologisch vooronderzoek uitgevoerd in een plangebied bij de Catherinakerk in Heusden (gemeente Heusden).
Rendering, B.J.
core   +1 more source