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Neural Induction and Neural Stem Cell Development
Regenerative Medicine, 2006Embryonic stem (ES) cells are a pluripotent and renewable cellular resource with tremendous potential for broad applications in regenerative medicine. Arguably the most important consideration for stem cell-based therapies is the ability to precisely direct the differentiation of stem cells along a preferred cellular lineage.
Lan T.H. Dang, Vincent Tropepe
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Immunomodulation by neural stem cells
Journal of the Neurological Sciences, 2008Neural (stem) cell transplantation has been proposed as a means of cell replacement therapy. Multipotential neural precursor cells (NPCs) that expand in floating spheres, and are (partially) committed to a glial fate, showed excellent remyelinating properties in a focal, chemically induced demyelinated lesion in the rat spinal cord.
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