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Efficacy and Safety of Crisugabalin (HSK16149) in Adults with Postherpetic Neuralgia

JAMA dermatology
Key Points Question What is the efficacy of crisugabalin, an oral calcium channel α2δ-1 subunit ligand, for postherpetic neuralgia? Findings In this randomized clinical trial of 366 adults, crisugabalin, 40 mg/d, and crisugabalin, 80 mg/d, for 12 weeks ...
Daying Zhang   +50 more
semanticscholar   +1 more source

Postherpetic Neuralgia

Neurologic Clinics, 1989
Although there is some variability (depending on the definition of postherpetic neuralgia), about 10% of those with zoster will have persisting pain 1 month after the rash.The main risk factor for postherpetic neuralgia is increasing age; it is uncommon in people aged 30% of those people aged >80 years.
openaire   +5 more sources

Postherpetic Neuralgia

2019
Postherpetic neuralgia (PHN) after acute herpes zoster ophthalmicus involves unilateral pain persisting or recurring for at least 3 months in the distribution of one or more branches of the trigeminal nerve. Patients often describe the pain associated with PHN as a deep aching or burning, dysesthetic, hyperesthetic, or electric shock-like sensation ...
Sebastian Rubino   +2 more
openaire   +1 more source

Analysis of the Risk Factors for Postherpetic Neuralgia

Dermatology, 2019
Background: Postherpetic neuralgia is the most common complication of herpes zoster, affecting 30% of patients. It seriously affects the quality of life of patients and the curative effect of treatment is limited.
Shijuan Wei   +4 more
semanticscholar   +1 more source

Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives

Current Pain and Headache Reports, 2023
Jiayu Tang   +4 more
semanticscholar   +1 more source

Sleep Shortage Is Associated With Postherpetic Neuralgia Development Through Hyperesthesia and Acute Pain Intensity: A Community‐Based Prospective Cohort Study

Pain Practice, 2019
There have been no community‐based studies investigating the association between sleep duration and postherpetic neuralgia (PHN) development. The aim of the current study was to examine the association of sleep with herpes zoster (HZ) incidence and PHN.
Keiko Yamada   +8 more
semanticscholar   +1 more source

[Postherpetic neuralgia].

Masui. The Japanese journal of anesthesiology, 2010
Varicella-zoster virus (VZV) causes two clinically distinct diseases: varicella and herpes zoster. Herpes zoster, recurrent infection of VZV occurs when the cell-mediated immunity to VZV declines. Since the cell-medicated immunity to VZV declines with aging, herpes zoster occurs more frequently in the elderly.
Kazuo, Higa   +2 more
openaire   +1 more source

Correlation between pain catastrophizing in acute herpes zoster and postherpetic neuralgia: a retrospective analysis

Journal of Anesthesia, 2023
Aki Fujiwara   +5 more
semanticscholar   +1 more source

Effects of Mindfulness-Based Stress Reduction on Depression, Anxiety, and Pain in Patients With Postherpetic Neuralgia.

Journal of Nervous and Mental Disease, 2019
The aim of this study was to explore the effects of mindfulness-based stress reduction (MBSR) on reducing the psychological and physical symptoms in patients with postherpetic neuralgia (PHN).
Xingmin Zhu   +8 more
semanticscholar   +1 more source

Postherpetic neuralgia

Neurology, 1962
A D, SEHGAL, W J, GARDNER
openaire   +2 more sources

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