Results 41 to 50 of about 38,340 (199)

Blockade of Glycine Transporter (GlyT) 2, but Not GlyT1, Ameliorates Dynamic and Static Mechanical Allodynia in Mice With Herpetic or Postherpetic Pain

Journal of Pharmacological Sciences, 2010
Glycine is an inhibitory neurotransmitter in the spinal dorsal horn and its extracellular concentration is regulated by glial glycine transporter (GlyT) 1 and neuronal GlyT2.
Yukitoshi Nishikawa, Atsushi Sasaki, Yasushi Kuraishi   +2 more
doaj   +1 more source

Interventional Treatments for Postherpetic Neuralgia: A Systematic Review.

Pain Physician, 2019
BACKGROUND Postherpetic neuralgia, a persistent pain condition often characterized by allodynia and hyperalgesia, is a deleterious consequence experienced by patients after an acute herpes zoster vesicular eruption has healed.
Chia-Shiang Lin, Ying-Chun Lin, H. Lao, C. Chen   +3 more
semanticscholar   +1 more source

Herpes Zoster and Postherpetic Neuralgia in an Elderly Patient with Critical COVID-19: A Case Report

Journal of Pain Research, 2020
Critical patients with COVID-19 are thought to be at high risk of developing chronic pain. However, the exact nature and mechanisms of COVID-19-related chronic pain remain largely unknown.
Xueqin Cao, Xianwei Zhang, W. Meng, Hua Zheng   +3 more
semanticscholar   +1 more source

Mirogabalin for the management of postherpetic neuralgia: a randomized, double-blind, placebo-controlled phase 3 study in Asian patients

Pain, 2019
This study investigated the safety and efficacy of mirogabalin, a novel, potent, selective ligand of the &agr;2&dgr; subunit of voltage-dependent Ca2+ channels, for the treatment of postherpetic neuralgia (PHN). In this multicenter, double-blind, placebo-
J. Kato, N. Matsui, Yoshihiro Kakehi, Emiko Murayama, S. Ohwada, M. Sugihara   +5 more
semanticscholar   +1 more source

Correlation between Galectin-3 and Early Herpes Zoster Neuralgia and Postherpetic Neuralgia: A Retrospective Clinical Observation

Pain Research and Management, 2020
This study aims to explore the value of serum galectin-3 in patients with herpes zoster neuralgia (HZN) and postherpetic neuralgia (PHN) and other factors influencing HZN and PHN occurrence. Samples from forty patients with herpes zoster neuralgia (HZN) (
Tingting Wang, Yong Fei, M. Yao, J. Tao, Jiajia Deng, Bing Huang   +5 more
semanticscholar   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Botulinum Toxin for Neuropathic Pain: A Review of the Literature

Toxins, 2015
Botulinum neurotoxin (BoNT), derived from Clostridium botulinum, has been used therapeutically for focal dystonia, spasticity, and chronic migraine. Its spectrum as a potential treatment for neuropathic pain has grown.
Hyun-Mi Oh, Myung Eun Chung
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Trigeminal ganglion electrical stimulation relieves refractory trigeminal herpes zoster and prevents postherpetic neuralgia: a case report

Journal of Medical Case Reports
Introduction Herpes zoster is an acute condition caused by the reactivation of varicella zoster virus, often affecting the skin and mucosa. When varicella zoster virus invades the trigeminal ganglion, it can lead to trigeminal herpes zoster, with ...
Wenhui Wu, Siwei Wang, Mo Zhou, Qian Ao, Jianhao Liao, Bangyong Qin, Jie Yuan   +6 more
doaj   +1 more source

Digital subtraction angiography-guided peripheral nerve stimulation via the foramen rotundum for refractory trigeminal postherpetic neuralgia: a case report and literature review

Frontiers in Neurology
Postherpetic neuralgia (PHN) is a debilitating complication of varicella-zoster virus infection. This case report presents a novel approach to treating refractory trigeminal maxillary postherpetic neuralgia using digital subtraction angiography (DSA ...
Qingbang Xu, Qingbang Xu, Qingbang Xu, Fangyuan Zhou, Fangyuan Zhou, Fangyuan Zhou, Dong Yang, Dong Yang, Dong Yang   +8 more
doaj   +1 more source