Results 121 to 130 of about 123,124 (300)

A review on radiochromic film dosimetry in radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 26, Issue 12, December 2025.
Abstract Radiochromic films (RCFs) are ubiquitous in radiation oncology clinical and research settings to measure the radiation dose over a two‐dimensional (2D) area due to their high spatial resolution, water‐equivalency, and relative ease‐of‐use. Upon irradiation, the constituent monomers of the active layer of RCFs undergo polymerization, leading to
Arash Darafsheh, Hamid Ghaznavi
wiley   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2569-2574, December 2025.
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit   +5 more
wiley   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

Clinical progress note: Varicella Zoster

open access: yesJournal of Hospital Medicine, Volume 20, Issue 12, Page 1348-1350, December 2025.
Abstract Varicella Zoster virus (VZV) is the etiologic agent responsible for varicella and herpes zoster (shingles). Nonimmune children and adults acutely infected with VZV typically experience a vesicular and pruritic rash that progresses from the face and trunk and generalizes to the extremities, accompanied by an oral enanthem along with symptoms of
Sirey Zhang, Adam L. Hersh, T. W. Jones
wiley   +1 more source

Mechanical Treatment of Common Neuropathic Itch Syndromes: A Retrospective Observational Evaluation of Mckenzie Method for Brachioradial Pruritus and Notalgia Paresthetica

open access: yesJEADV Clinical Practice, Volume 4, Issue 5, Page 1075-1081, December 2025.
In case a mechanical disco‐radicular conflict is at the base of BRP or NP, a spine‐directed approach in line with the McKenzie method is found to alleviate symptoms. ABSTRACT Background Brachioradial pruritus (BRP) and notalgia paresthetica (NP) are neuropathic itch syndromes that are often challenging to treat, typically managed within a ...
Patrick Van den Eynde   +4 more
wiley   +1 more source

Progression and Metastasis of Lung Cancer: Clinical Features, Molecular Mechanisms, and Clinical Managements

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Lung cancer represents a significant global health threat. Despite progress in treatment, metastasis continues to present a major clinical challenge. This article reviews the metastases of lung cancer to the liver, bone, and brain, focusing on clinical symptoms, molecular mechanisms, and treatment strategies.
Yunkui Zhang   +4 more
wiley   +1 more source

An Unusual Presentation of Herpes Zoster [PDF]

open access: yes, 2020
Cristiano, Peter   +3 more
core   +2 more sources

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Shingles & Pneumococcal Vaccines: Recommendations for Older Adults [PDF]

open access: yes, 2018
As the immune system tends to weaken over time, patients aged 50+ begin having increased risk for certain potentially preventable diseases, especially shingles and pneumonia.
Flinn, Benjamin
core   +1 more source

To Assess Cases of Trigeminal Neuralgia

open access: bronze, 2020
Alankrita Chaudhary   +4 more
openalex   +2 more sources

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