Results 151 to 160 of about 123,429 (310)

Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain

open access: yesArquivos de Neuro-Psiquiatria
Neuropathic pain is a chronic pain condition caused by damage or dysfunction of the central or peripheral nervous system. Electroacupuncture (EA) has an antinociceptive effect on neuropathic pain, which is partially due to inhibiting astrocyte activation
Mingxiao Zhang   +8 more
doaj   +1 more source

Mechanical Treatment of Common Neuropathic Itch Syndromes: A Retrospective Observational Evaluation of Mckenzie Method for Brachioradial Pruritus and Notalgia Paresthetica

open access: yesJEADV Clinical Practice, Volume 4, Issue 5, Page 1075-1081, December 2025.
In case a mechanical disco‐radicular conflict is at the base of BRP or NP, a spine‐directed approach in line with the McKenzie method is found to alleviate symptoms. ABSTRACT Background Brachioradial pruritus (BRP) and notalgia paresthetica (NP) are neuropathic itch syndromes that are often challenging to treat, typically managed within a ...
Patrick Van den Eynde   +4 more
wiley   +1 more source

Local anesthetic infiltration vs. nervous blocks in face’s skin lesions: what’s new [PDF]

open access: yes, 2018
Skin tumors are the most common type of cancer. They are localized throughout the body, more frequently in those regions chronically exposed to sun, like face, scalp and neck, compromising aesthetic appearance.
Arrico, L.   +4 more
core  

Progression and Metastasis of Lung Cancer: Clinical Features, Molecular Mechanisms, and Clinical Managements

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Lung cancer represents a significant global health threat. Despite progress in treatment, metastasis continues to present a major clinical challenge. This article reviews the metastases of lung cancer to the liver, bone, and brain, focusing on clinical symptoms, molecular mechanisms, and treatment strategies.
Yunkui Zhang   +4 more
wiley   +1 more source

Low back pain

open access: yesRevista Dor
BACKGROUND AND OBJECTIVES: Neuropathic pain is present in 37 to 55% of cases of low back pain. Neuropathic pain is associated with more intense pain, more severe comorbidities and worse quality of life.
Patrick Raymond Nicolas André Ghislain Stump   +2 more
doaj   +1 more source

Use of anticonvulsants drugs for neuropathic painful conditions [PDF]

open access: yes, 2008
Neuropathic pain, a form of chronic pain initiated and sustained by an insult to the peripheral or central nervous system, is a challenge to clinicians as it does not respond well to traditional pain therapies.
Afshan, Gauhar, Hussain, Aziza Mohammad
core   +1 more source

Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Along with organismal aging or pathogenic processes especially tumor, multiple immune cell types exhibit those well‐established hallmarks of cellular senescent phenotype, mainly characterized by irreversible cell cycle arrest, metabolic disorder, and over production of SASP.
Ninghan Gong   +8 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

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