Results 41 to 50 of about 59,055 (217)

HLA‐B*15:21 carrier status is a susceptibility factor of carbamazepine‐induced nonimmediate cutaneous adverse reactions in HLA‐B*15:02‐negative patients: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon, Chutima Seree‐aphinan, Antida Sangiemchoey, Khwanchanok Kaewpiboon, Taweesak Maneerot, Oradawan Plong‐on, Pornsiri Sangmanee, Punthipa Nichanon, Jariya Khayman, Jiraphan Manee, Areerat Hnoonual, Kanoot Jaruthamsophon   +11 more
wiley   +1 more source

A retrospective study of the correlation between herpes zoster neuralgia and the serum neuron-specific enolase level in the largest dermatological hospital in Zhejiang province, China

Frontiers in Immunology, 2022
We studied the changes and clinical significance of the serum neuron-specific enolase (NSE) level in peripheral blood of patients with post-herpetic neuralgia (PHN).Material and methodsPatients with PHN were divided into a mild PHN group and a severe PHN
Changyang Zhong, Ding Lin, Yuan Liu, Chunli Wu   +3 more
doaj   +1 more source

Translational development of crisugabalin for neuropathic pain

British Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João, Jilly Octoria Tagore Chan, Luísa Mendes Araújo, André Batista João, Raquel Mattos Filgueiras, Paulo César Ragazzo   +5 more
wiley   +1 more source

Neuralgia do trigêmeo: análise dos resultados do tratamento por compressão percutânea com balão no gânglio de gâsser [PDF]

, 2004
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Campos, Wuilker Knoner
core  

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Primary care incidence and treatment of four neuropathic pain conditions: A descriptive study, 2002–2005

BMC Family Practice, 2008
Background Between 1992 and 2001 the UK general practice incidence of post-herpetic neuralgia and trigeminal neuralgia declined, whilst the incidence of painful diabetic neuropathy increased. The most common first line treatments were compound analgesics.
Carroll Dawn, Hall Gillian C, McQuay Henry J   +2 more
doaj   +1 more source

A Systematic Review on Cannabinoids for Neuropathic Pain Administered by Routes Other than Oral or Inhalation

Plants, 2022
The use of cannabis and cannabinoid products for the treatment of neuropathic pain is a growing area of research. This type of pain has a high prevalence, limited response to available therapies and high social and economic costs.
Jose-Manuel Quintero, German Pulido, Luis-Fernando Giraldo, Marta-Ximena Leon, Luis-Eduardo Diaz, Rosa-Helena Bustos   +5 more
doaj   +1 more source

Pharmacotherapy of Trigeminal neuralgia

, 2023
Trigeminal neuralgia (TN) is a chronic neuropathic pain disorder characterized by recurrent paroxysmal electric shock-like or stabbing pain within the distribution of one or more divisions of the trigeminal nerve.
Nwoguwgwu, Ezinne Uche
core  

Semiology of functional/dissociative seizures in idiopathic generalized epilepsy: An inpatient video‐electroencephalographic study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to estimate the prevalence and characterize the semiology of co‐occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video‐electroencephalography (video‐EEG)‐diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE ...
Javier Peña‐Ceballos, Kishen Radhakrishna, Tenzin Choekyi, Clodagh O'Keeffe, Mohamed Ali, Alma O'Donnell, Tudor Munteanu, Patrick B. Moloney, Hany El Naggar, Gerard Mullins, Peter Widdess‐Walsh, Ronan D. Kilbride, Norman Delanty, Nuala McNicholas   +13 more
wiley   +1 more source

Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

Frontiers in Integrative Neuroscience, 2018
Herpes zoster or shingles is the result of varicella zoster virus (VZV) infection and often results in chronic pain that lasts for months after visible symptoms subside. Testosterone often attenuates pain in males.
Phillip R. Kramer, Mahesh Rao, Crystal Stinson, Larry L. Bellinger, Paul R. Kinchington, Michael B. Yee   +5 more
doaj   +1 more source