Detection of N-glycolyl-neuraminic acid-containing glycolipids in human skin [PDF]
Frontiers in Immunology, 2023 Humans lack the enzyme that produces the sialic acid N-glycolyl neuraminic acid (Neu5Gc), but several lines of evidence have shown that Neu5Gc can be taken up by mammalian food sources and replace the common human sialic acid N-acetyl neuraminic acid ...
Michela Manni +10 more
doaj +4 more sources
Safety of synthetic N‐acetyl‐d‐neuraminic acid as a novel food pursuant to Regulation (EC) No 258/97 [PDF]
EFSA Journal, 2017 Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on synthetic N‐acetyl‐d‐neuraminic acid (NANA) as a novel food (NF) submitted pursuant to ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) +27 more
doaj +7 more sources
Designing and Development of FRET-Based Nanosensor for Real Time Analysis of N-Acetyl-5-Neuraminic Acid in Living Cells [PDF]
Frontiers in Nutrition, 2021 N-acetyl-5-neuraminic acid (NeuAc) plays crucial role in improving the growth, brain development, brain health maintenance, and immunity enhancement of infants.
Ruphi Naz +7 more
doaj +4 more sources
Shift of the reaction equilibrium at high pressure in the continuous synthesis of neuraminic acid [PDF]
Beilstein Journal of Organic Chemistry, 2022 The importance of a compound that helps fight against influenza is, in times of a pandemic, self-evident. In order to produce these compounds in vast quantities, many researchers consider continuous flow reactors in chemical industry as next stepping ...
Jannis A. Reich +5 more
doaj +2 more sources
Kinetic characterization of two neuraminic acid synthases and evaluation of their application potential [PDF]
Applied Microbiology and BiotechnologyMehmet Mervan Čakar +2 more
exaly +4 more sources
One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase [PDF]
Frontiers in Microbiology, 2023 N-acetylneuraminic acid (Neu5Ac) possesses the ability to promote mental health and enhance immunity and is widely used in both medicine and food fields as a supplement.
Quanzhen Liu +6 more
doaj +2 more sources
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides [PDF]
Frontiers in Immunology, 2019 Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Anoopjit Singh Kooner, Hai Yu, Xi Chen
doaj +4 more sources
Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis [PDF]
Applied and Environmental MicrobiologyWhole-cell biosensors (WCBs) can leverage the physiology of engineered bacteria in vivo to detect target molecules of interest. Detection of these analytes via minimally invasive sampling of biological fluids such as saliva will improve early detection ...
Samuel J. Verzino +14 more
doaj +2 more sources
Understanding the Effects of Lactose Hydrolysis Modeling on the Main Oligosaccharides in Goat Milk Whey Permeate [PDF]
Molecules, 2019 Enzymatic hydrolysis of lactose is a crucial step to improve the efficiency and selectivity of membrane-based separations toward the recovery of milk oligosaccharides free from simple sugars.
Caroline Thum +5 more
doaj +4 more sources
Production of
BMC Biotechnology, 2009 Background Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as double-tagged gene fusions.
Cheng Chung-Hsien +5 more
doaj +3 more sources