Results 31 to 40 of about 10,995 (256)
Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]
, 2010 Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
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Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili
Nature Communications, 2019 Meningococcus utilizes β-arrestin selective activation of endothelial cell β2 adrenergic receptor (β2AR) to cause meningitis in humans. Here authors report that Meningococcus triggers β2AR signaling by exerting forces on β2AR glycans that terminally ...
Zoe Virion +11 more
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Laboratory Animal Research, 2016 Helicobacter pylori colonizes the gastric mucosa of about half of the world’s population, causing chronic gastritis and gastric cancer. An increasing emergence of antibiotic-resistant H. pylori arouses demand on alternative non-antibiotic-based therapies.
Dong-Jae Kim +6 more
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Glycosylated proteins preserved over millennia: N-glycan analysis of Tyrolean Iceman, Scythian Princess and Warrior. [PDF]
, 2014 An improved understanding of glycosylation will provide new insights into many biological processes. In the analysis of oligosaccharides from biological samples, a strict regime is typically followed to ensure sample integrity.
An, Hyun Joo +11 more
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Immune response to racotumomab in a child with relapsed neuroblastoma
Frontiers in Oncology, 2012 Immunotherapy targeting ganglioside antigens is a powerful tool for the treatment of high risk neuroblastoma. However, only treatment with anti-GD2 antibodies has been used in clinical practice and other options may be pursued.
CLAUDIA VANESA SAMPOR +11 more
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Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors [PDF]
, 2014 Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV). Neu5Gc is synthesized from Neu5Ac by the enzyme
Böhm, Raphael +14 more
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Scientific Reports, 2017 Human parainfluenza viruses represent a leading cause of lower respiratory tract disease in children, with currently no available approved drug or vaccine.
Larissa Dirr +4 more
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Preparation of radioactive Tay-Sachs ganglioside labeled in the sialic acid moiety
Journal of Lipid Research, 1970 A procedure is described for the preparation of Tay-Sachs ganglioside specifically labeled in the sialic acid portion of the molecule. Rat brain gangliosides were labeled biosynthetically by the intracranial injection of N-acetyl-(3)H-D-mannosamine ...
E.H. Kolodny +3 more
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Comparison of four different algorithms for the calculation of radioimmunoassay standard curves [PDF]
, 1980 Peer ...
Herndl, R. +2 more
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Sphingolipid composition of human platelets
Journal of Lipid Research, 1973 Total lipid extracts from washed trypsinized human platelets were fractionated into neutral lipids, glycosphingolipids, and phosphclipids by silicic acid chromatography.
Robert V.P. Tao +2 more
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