Results 41 to 50 of about 10,995 (256)

Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

open access: yesBeilstein Journal of Organic Chemistry, 2010
Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal
Arne Homann   +4 more
doaj   +1 more source

Abnormal gangliosides in Tay-Sachs disease, Niemann-Pick's disease, and gargoylism

open access: yesJournal of Lipid Research, 1966
The molar ratios of N-acetyl neuraminic acid, hexose, hexosamine, and sphingosine have been determined for the abnormal ganglioside in Tay-Sachs disease that was previously detected as a fast-moving band in thin-layer chromatography, and in two abnormal ...
D.A. Booth, H. Goodwin, J.N. Cumings
doaj   +1 more source

In vitro increased respiratory activity of selected oral bacteria may explain competitive and collaborative interactions in the oral microbiome [PDF]

open access: yes, 2017
Understanding the driving forces behind the shifts in the ecological balance of the oral microbiota will become essential for the future management and treatment of periodontitis. As the use of competitive approaches for modulating bacterial outgrowth is
Boon, Nico   +6 more
core   +3 more sources

Whole Genome Sequencing and Multiplex qPCR Methods to Identify Campylobacter jejuni Encoding cst-II or cst-III Sialyltransferase

open access: yesFrontiers in Microbiology, 2018
Campylobacter jejuni causes more than 2 million cases of gastroenteritis annually in the United States, and is also linked to the autoimmune sequelae Guillan–Barre syndrome (GBS).
Jason M. Neal-McKinney   +4 more
doaj   +1 more source

Glycolyl-neuraminic Acid in Ox Brain Gangliosides [PDF]

open access: yesNature, 1965
IN this communication we report the presence of glycolyl-neuraminic acid in sialic acids from ox brain gangliosides. Our method of analysis consisted of the following six steps: (i) gangliosides were extracted from ox brain grey matter and purified according to a method which we have previously described1; (ii) gangliosides so obtained were hydrolysed ...
G, Tettamanti   +3 more
openaire   +2 more sources

Insights into the evolution of sialic acid catabolism among bacteria [PDF]

open access: yes, 2009
Background Sialic acids comprise a family of nine-carbon amino sugars that are prevalent in mucus rich environments. Sialic acids from the human host are used by a number of pathogens as an energy source.
Salvador Almagro-Moreno, E Fidelma Boyd
core   +2 more sources

Carbohydrates of Bovine α-Lactalbumin Preparations

open access: yesCHIMIA, 1971
D-mannose, D-galactose, 2-acetamido-2-deoxy-D-galactose, 2-acetamido-2-deoxy-D-glucose and N-acetyl neuraminic acid have been identified in preparations of bovine a-lactalbumin.
E.J. Hindle, J.V. Wheelock
doaj   +1 more source

Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection. [PDF]

open access: yes, 2019
Streptococcus gordonii and Streptococcus sanguinis are primary colonizers of the tooth surface. Although generally non-pathogenic in the oral environment, they are a frequent cause of infective endocarditis.
Barnard, Karen N   +10 more
core   +3 more sources

Sialic Acid, Ferritin and CEA Levels in Peripheral Blood and Blood Draining from the Tumor in Breast Cancer

open access: yesThe International Journal of Biological Markers, 1988
Concentrations of total serum N-acetyl-neuraminic acid, carcinoembryonic antigen, ferritin, lactate dehydrogenase, creatine phosphokinase and total proteins were measured in both tumor drainage blood (axillary vein) and in peripheral blood taken during ...
M. Monti   +5 more
doaj   +1 more source

Mass spectrometry of neutral, mono- and disialoglycosphingolipids

open access: yesJournal of Lipid Research, 1971
Microgram quantities of complex glycosphingolipids were fully trimethylsilylated and analyzed by mass spectrometry. Reproducible ratios of the intensities of certain sugar fragment ions to the total intensity of ions characteristic of the sphingolipid ...
GLYN DAWSON, CHARLES C. SWEELEY
doaj   +1 more source

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