Results 101 to 110 of about 56,674 (254)
A longitudinal study of abnormalities on MRI and disability from multiple sclerosis
Background: In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T2-weighted magnetic resonance imaging (MRI) of ...
Ciccarelli, O. +5 more
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Inferior Vestibular Neuritis: Diagnostic Criteria, Clinical Features, and Prognosis—A Focused Review
Purpose: This review aims to analyze the diagnostic methods used to evaluate inferior vestibular nerve neuritis. Methods: We performed an electronic search on the PubMed database for clinical studies investigating the diagnostic techniques used for ...
Gabriela Cornelia Musat +7 more
doaj +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Variation in Evolving Optic Neuritis
The typical natural history of optic neuritis is subjected to important exceptions. Recognition of these exceptions has led to valuable insights regarding specific etiologies of optic neuritis.
Marc A. Bouffard, MD; Robert M. Mallery, MD; Yaping J. Liao, MD, PhD; Nurhan Torun, MD
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The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert +13 more
wiley +1 more source
Optic neuritis as an early sign of multiple sclerosis
Nilufer Kale Department of Neurology, Bakirkoy Prof Dr Mazhar Osman Training and Research Hospital, Istanbul, Turkey Abstract: Optic neuritis (ON) is an acute inflammatory demyelinating disorder of the optic nerve. The general characteristics of isolated
Kale N
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Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik +4 more
wiley +1 more source
Historical Perspective on the Diagnosis and Treatment of Optic Neuritis
Reviewing the history of the diagnosis and treatment of optic neuritis allows for a unique perspective on this disorder and more importantly helps to highlight the critical point in time that we are now at concerning this diagnosis, its prognosis and ...
Nicholas J. Volpe
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Background: Optic neuritis is an inflammation of the optic nerve. Because of importance of vision for human, management of optic neuritis is an important issue in neurology.
Seyed-Ehsan Mohammadianinejad +6 more
doaj

