Results 151 to 160 of about 94,511 (305)

Risk Prediction of a Multiple Sclerosis Diagnosis

, 2013
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease.
Ghosh, Joydeep, Ho, Joyce C., Unnikrishnan, KP   +2 more
core   +1 more source

Humanized Mouse Models for Type 1 Diabetes

Current Protocols, Volume 5, Issue 10, October 2025.
Abstract T cell–mediated autoimmune type 1 diabetes (T1D) is under complex polygenic control in both humans and the NOD mouse model. However, in both species, particular major histocompatibility complex (MHC; designated HLA in humans) haplotypes provide the primary T1D risk factor. Both MHC/HLA class I and II variants interactively contribute to T1D by
David V. Serreze, Marissa Tousey‐Pfarrer, Jeremy J. Racine   +2 more
wiley   +1 more source

Clinical Lecture on Two Cases of Malarial Neuritis with Tremors [PDF]

, 1897
Alex James
openalex   +1 more source

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue

Journal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Leandro Mantovani de Castro, Elaine Raniero Fernandes, Juarez Antonio Simoes Quaresma, Carmen Lucia Penteado Lancelotti, Maria Irma Seixas Duarte, Leda Viegas de Carvalho, Ricardo Penny, Pedro Fernando da Costa Vasconcelos, Evandro Sobroza de Mello, Mirian Nacagami Sotto, Carla Pagliari   +10 more
wiley   +1 more source

Revisiting the “Tram-Track” sign

Indian Journal of Ophthalmology, 2017
Akshay Gopinathan Nair, Veena R Iyer, Indumati Gopinathan   +2 more
doaj   +1 more source

Isolierte Neuritis vestibularis nach Typhusschutzimpfung²) [PDF]

, 1915
Caesar Hirsch
openalex   +1 more source

Otopathologic Patterns of Cellular Degeneration in the Peripheral Vestibular Organ Secondary to Head Trauma

The Laryngoscope, Volume 135, Issue 10, Page 3859-3866, October 2025.
This study examines vestibular degeneration following head trauma, comparing cases with and without fractures. Histopathological analysis of 26 temporal bones showed more severe damage in nonfracture cases, particularly in Scarpa's ganglion cells and vestibular hair cells.
Tomotaka Shimura, Mio Takeuchi, Nevra Keskin Yilmaz, Dilshan Rajan, Sebahattin Cureoglu, Sei Kobayashi, Rafael da Costa Monsanto   +6 more
wiley   +1 more source

The clinical profile of new-onset optic neuritis in arabs, a tertiary center experience in Kuwait

Heliyon
Background: Optic neuritis is an inflammatory disorder of the optic nerve and is often the initial manifestation of systemic demyelinating diseases such as multiple sclerosis (MS), neuromyelitis optic spectrum disorder (NMOSD), and myelin-oligodendrocyte
Raed Behbehani, Abdullah Ali, Ahmed Alakool, Samar Farouk, Raed Alroughani   +4 more
doaj   +1 more source

OPTIC NEURITIS IN CHLOROSIS [PDF]

, 1910
C. O. Hawthorne
openalex   +1 more source

Targeting the Ubiquitin–Proteasome System for Cancer

MedComm, Volume 6, Issue 10, October 2025.
This figure shows the mechanism of protein degradation by ubiquitin–proteasome system. The process begins with ubiquitin activation by the E1 enzyme, forming a thioester bond between E1's cysteine residue and ubiquitin's glycine carboxyl group, powered by ATP hydrolysis.
Zhaoyun Liu, Jiao Lai, Ziyu Ma, Jianhua Pan, Chun Yang, Rong Fu   +5 more
wiley   +1 more source