Results 141 to 150 of about 362 (162)

Ocular pathology in NeuroAIDS – An autopsy study

Experimental Eye Research, 2020
The central nervous system (CNS) and the eye are involved in Human immunodeficiency virus related disease. Although, optic nerve is considered an extension of the CNS, it has not been systematically evaluated to determine if infections of brain can extend into the eye or vice versa. The brain and posterior compartment of eyeball retrieved at autopsy of
Radhika, Mhatre, Sunil, Govekar, Nandeesh, Bn, Latha P, Lakshman, Ravikumar, Banda, Satishchandra, P, Shankar, Sk, Mahadevan, Anita   +7 more
openaire   +2 more sources

Neuroimmunity, Drugs of Abuse, and neuroAIDS

Journal of Neuroimmune Pharmacology, 2006
It has long been postulated that drugs of abuse may represent significant cofactors in the progression of human immunodeficiency virus (HIV)-induced disease. Both HIV infection and drugs of abuse have significant effect on the immune system as well as on the nervous system.
Tricia H, Burdo, Simon N, Katner, Michael A, Taffe, Howard S, Fox   +3 more
openaire   +2 more sources

Survival after neuroAIDS

Neurology, 2011
We examined if the CNS Penetration-Effectiveness (CPE) score of antiretroviral drugs was associated with survival after a diagnosis of HIV-related encephalopathy, progressive multifocal leukoencephalopathy (PML), cerebral toxoplasmosis, or cryptococcal meningitis.Using data from the FHDH-ANRS CO4, we compared the survival of 9,932 HIV-infected patients
Lanoy, Emilie, Guiguet, Marguerite, Bentata, M., Rouveix, Elisabeth, Dhiver, C., Poizot-Martin, Isabelle, Costagliola, Dominique, Gasnault, J., Michelet, Christian   +8 more
openaire   +3 more sources

NeuroAIDS: virological aspects of HIV infection.

Journal of biological regulators and homeostatic agents, 2013
NeuroAIDS is one of the main complications of chronic HIV-infection. The Central Nervous System is an immunologic sanctuary for HIV and allows the persistence of the virus despite an efficient antiretroviral therapy. HIV-1 could promote the neurodegeneration through the induction of inflammation by the release of neurotoxins from infected cells.
Surdo, M, Cortese, M, PERNO, CARLO FEDERICO, AQUARO, STEFANO   +3 more
openaire   +4 more sources

Global Issues in NeuroAIDS

2017
Neurological manifestations and sequelae of HIV infection are extensive. Direct neurological manifestations of disease, affecting the central and peripheral nervous systems, vary with progressive immune compromise and probably disease duration. Indirect or secondary neurological complications of HIV include infective, hematological, malignant, vascular,
Jennifer Massey, Bruce Brew
openaire   +1 more source

Emerging views of NeuroAIDS

The Lancet Neurology, 2008
More than 40 million people are infected with human immunodefi ciency virus type 1 (HIV-1), with an estimated death toll of over 3·5 million. Despite preventive eff orts, the epidemic continues to spread, and more than 20% of all individuals infected with HIV will develop neurological complications.
openaire   +1 more source

GFP-Lentiviral Vectors Targeting for NeuroAIDS

2009
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired immunodeficiency syndrome (AIDS). HIV-1 can infect human brain macrophages and microglial cells, causing HIV-associated dementia, or neuroAIDS, an increasingly common disorder of the central nervous system (CNS) that affects 20% of HIV-1-infected individuals.
openaire   +2 more sources

Gene Therapy Blueprints for NeuroAIDS

2017
Since the start of the HIV/AIDS pandemic, 37 years ago, early work produced evidence for CNS involvement and that HIV-1B infection could penetrate the brain. Since then, a plethora of studies further identified many host proteins, RNAs, and genes implicated in brain involvement consequent to HIV-1B infection.
Hector E. Rodriguez, Seetha Lakshmi, Charurut Somboonwit, Asa Oxner, Lucy Guerra, Anteneh Addisu, Louise Gutierrez, John T. Sinnott, Christina Nilofer, Pandjassarame Kangueane, Paul Shapshak   +10 more
openaire   +1 more source

Oxidative stress and neuroAIDS

Trends in neurosciences, 2001
Neurological disorders represent one of the most common disturbances accompanying HIV infection. In the past few years, highly antiretroviral active therapy has significantly reduced the incidence of HIV-related diseases. However, neurological dysfunction in AIDS patients still remains an unresolved problem.
Mollace, [No Value], Nottet, HSLM, Clayette, P, Turco, MC, Muscoli, C, Salvemini, D, Perno, CF   +6 more
openaire   +1 more source

EEG biomarkers of NeuroAIDS

Clinical Neurophysiology, 2014
Ryouhei, Ishii, Leonides, Canuet
openaire   +2 more sources