Unusual presentation of neurobrucellosis presenting with the features of parkinsonism: two case reports and a review of the literature [PDF]
BackgroundBrucellosis, a zoonotic disease caused by Brucella species, remains endemic in regions such as Saudi Arabia. While neurobrucellosis is a serious complication, its presentation with parkinsonian features and psychiatric manifestations is ...
Moneera Aldraihem +8 more
doaj +2 more sources
An unusual case of neurobrucellosis with intracranial hypertension and bilateral abducens nerve palsy [PDF]
Background Brucellosis is one of the most common zoonotic diseases in the world and it can affect many systems. Rarely, central nervous system involvement, which is a serious complication, can be observed.
Bahar Kandemir +6 more
doaj +2 more sources
Motor polyradiculoneuropathy as an unusual presentation of neurobrucellosis: a case report and literature review [PDF]
Brucellosis, a zoonotic disease caused by Brucella species, poses a significant global health concern. Among its diverse clinical manifestations, neurobrucellosis remains an infrequent yet debilitating complication.
Ahmad Alikhani +3 more
doaj +2 more sources
Neurobrucellosis with negative serological examination: a case report and literature review [PDF]
Neurobrucellosis is an uncommon occurrence that can arise as a consequence of brucellosis. However, its clinical symptoms are severe and have the potential to be life-threatening.
Boyao Yuan +3 more
doaj +2 more sources
Brucella suis S2 strain inhibits IRE1/caspase-12/caspase-3 pathway-mediated apoptosis of microglia HMC3 by affecting the ubiquitination of CALR [PDF]
Neurobrucellosis represents a severe complication of brucellosis, posing a considerable risk to human health and quality of life. This condition arises from an increased susceptibility to chronic Brucella infection, a significant clinical challenge.
Zhao Wang +4 more
doaj +2 more sources
Neurobrucellosis and Multiple Sclerosis: Cause, Confounder, or Coincidence? [PDF]
We report the case of a 17-year-old girl who was initially diagnosed with multiple sclerosis based on clinical and radiological findings and later confirmed to have neurobrucellosis via cerebrospinal fluid Brucella polymerase chain reaction positivity ...
Burak Kocaaga +4 more
doaj +2 more sources
Neurobrucellosis: a retrospective cohort of 106 patients. [PDF]
Abstract Background Neurobrucellosis, a serious central nervous system infection caused by Brucella species, presents significant challenges due to its diverse clinical manifestations and the risk of long-term complications and poor outcomes. Identifying predictors of adverse outcomes is critical for improving patient
Arazi F +4 more
europepmc +5 more sources
Neurobrucellosis is a complication of brucellosis, which is considered endemic in the Indian subcontinent, Arabian Peninsula and Mediterranean countries.
Mohamed Ata Hendaus +2 more
doaj +2 more sources
Demyelinating Neurobrucellosis Presenting With Neuropsychiatric Manifestations. [PDF]
Neurobrucellosis with psychiatric manifestations is an uncommon manifestation of brucellosis. Herein, we report a 31‐year‐old male complaining of dizziness, nausea, malaise, imbalance, amnesia, psychosis, delusion, and impulsive and disorganized behavior.
Varshochi M, Ravanbakhsh Ghavghani F.
europepmc +2 more sources
BvrR From Brucella abortus Induces Neuroinflammation Through IRE1-Mediated Activation of ATF2 and NF-κB. [PDF]
This study demonstrates that the BvrR induces neuroinflammation. In microglial cells, BvrR expression localizes to the endoplasmic reticulum (ER), causing ER expansion and activating the stress sensor IRE1. Phosphorylated IRE1 subsequently drives the activation and nuclear translocation of transcription factors ATF2 and NF‐κB p65.
Wang Z, Yu X, Liu B, Ren D.
europepmc +2 more sources

