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Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Adverse social conditions across the life course influence brain aging and dementia, yet their compounded impact on clinical phenotypes remains underexplored, particularly in Latin America, where social inequality and dementia burden are high.
Temitope Farombi +36 more
wiley +1 more source

Astrocitoma pilocítico cerebeloso Estudio de cohorte retrospectivo evaluando el resultado funcional postoperatorio, el mutismo y la hidrocefalia.

, 2022
Objetivo: Analizar una serie de pacientes pediátricos con APc evaluando factores que puedan modificar el desenlace en cuanto a “outcome” neurológico, mutismo e hidrocefalia.Materiales y métodos: Estudio unicéntrico, de cohorte retrospectivo, de pacientes
Giovannini, Sebastián Juan María +3 more
core

Pharmacological management of tauopathies [PDF]

Alzheimers Dement
Abstract Tauopathies, a group of neurodegenerative disorders characterized by tau protein aggregation, encompass diseases such as progressive supranuclear palsy, and corticobasal degeneration. While the development of disease‐modifying therapies remains a primary research focus, current pharmacological interventions are predominantly directed towards ...
Rioja R +5 more
europepmc +2 more sources

Manejo de la anticoagulación y tromboprofilaxis en paciente con patología neuroquirúrgica [PDF]

Revista Chilena de Anestesia, 2023
Joel Marchant K. +3 more
doaj +1 more source

Efficacy and Safety of the Use of Interspinous Spacers in the Treatment of Lumbar Spinal Stenosis: Mapping Gap and Scoping Review

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Objectives Low back pain is a common pathology in the general population. In people over 60 years of age, it is associated with degenerative changes that cause narrowing of the vertebral canal. Its treatment includes conservative measures and even surgery with decompression and fusion.
Juan Carlos Acevedo‐Gonzalez +3 more
wiley +1 more source

Mapping the neurovascular landscape in aging and dementia: cerebral small vessel disease markers in a multicenter Latin American cohort

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Cerebral small vessel disease (CSVD) is a key contributor to cognitive impairment and dementia, yet few studies have compared CSVD across dementia variants, particularly in underrepresented populations. METHODS In a multicenter cross‐sectional study, we analyzed magnetic resonance imaging (MRI) markers of CSVD, including white ...
Florencia Altschuler +24 more
wiley +1 more source

Dr. Donald Morote Revolledo

Acta Médica Peruana, 2018
Insigne hijo de Arequipa, el Dr. Donald Morote Revolledo nació en 1928. Líder innato y académico polifacético, participó tanto en actividades docentes, asistenciales como políticas.
Edgar Morales Landeo
doaj

Recommendations for genetic counseling for individuals at risk of autosomal dominant Alzheimer's disease in Latin America

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering predictive testing for known familial variants.
Daniel A. Jiménez +26 more
wiley +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Asistencia Endoscópica en la Descompresión Microquirúrgica del Hemiespasmo Facial

, 2020
Introducción: El hemiespasmo facial primario (HFP) se produce por la hiperexcitabilidad del nervio facial y sus núcleos de origen como consecuencia de la compresión vascular.
Cervio, Andrés Eduardo +5 more
core

neurosurgery
fmri