Results 91 to 100 of about 629,232 (383)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Neuropsychiatric and Neurocognitive Manifestations in HIV-Infected Children Treated With Efavirenz in South Africa—A Retrospective Case Series

Frontiers in Neurology, 2019
Background: Efavirenz is associated with transient neuropsychiatric manifestations but the impact on neurocognition in children is unknown. Genetically slow metabolizers of efavirenz may be at risk of toxicity.
Charles K. Hammond, Charles K. Hammond, Brian Eley, Natalia Ing, Jo M. Wilmshurst   +4 more
doaj   +1 more source

Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals. [PDF]

, 2011
We explored the possible augmenting effect of traumatic brain injury (TBI) history on HIV (human immunodeficiency virus) associated neurocognitive complications.
Atkinson, J Hampton, CHARTER group, Clifford, David, Collier, Ann C, Ellis, Ronald J, Fennema-Notestine, Christine, Franklin, Donald, Gelman, Benjamin, Grant, Igor, Heaton, Robert, Jernigan, Terry, Lin, Kenny, Marra, Christina, McArthur, Justin, McCutchan, Allen, Morgello, Susan, Simpson, David, Taylor, Michael J   +17 more
core   +3 more sources

Prospective MRI and Neurocognitive Assessment of “Chemobrain” in Acute Myeloid Leukaemia: The Mineral Study [PDF]

, 2023
Ashleigh Scott, Ada Lo, Kate Thompson, Ying Xia, Harriet L Bodimeade, Amir Fazlollahi, Cameron Curley, Steven Lane, Kirk Morris, Caroline McNamara, Elango Pillai, N Weber, Olivier Salvado, Katie L. McMahon, Glen Kennedy   +14 more
openalex   +1 more source

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang, Chunyan Xiang, Liangxiao Zhang, Peiwu Li   +3 more
wiley   +1 more source

EXPLORING SUBSTANCE USE AND HIV TREATMENT FACTORS ASSOCIATED WITH NEUROCOGNITIVE IMPAIRMENT AMONG PEOPLE LIVING WITH HIV/AIDS

Frontiers in Public Health, 2014
Neurocognitive (NC) impairment remains prevalent among people living with HIV (PLWH) and may be exacerbated by alcohol and drug use. This cross-sectional study assesses the degree to which alcohol and other drug use, time from HIV diagnosis to treatment,
Jennifer M Attonito, Jessy G. Devieux, Brenda D.G. Lerner, Michelle M. Hospital, Rhonda eRosenberg   +4 more
doaj   +1 more source

Reply: Methotrexate neurotoxicity due to drug interactions: an inadequate folinic acid effect [PDF]

, 2017
No abstract ...
Baird, Susan F., Forster, Victoria J., Halsey, Christina, Mair, Shona, Skinner, Roderick, van Delft, Frederik W.   +5 more
core   +1 more source

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes, Álvaro Martín‐Rodríguez, Miguel Del Campo, Lynne M. Bird   +3 more
wiley   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Frequency of low ImPACT scores among adolescent and young adult student-athletes with attention-deficit/hyperactivity disorder and/or learning disorder

Frontiers in Neurology
IntroductionAttention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by attention problems, excessive activity, and impulsivity - occurring in approximately 13% of children 12–17 years of age, and as many as 16% of ...
Philip Schatz, John Cuzzupe, Justin E. Karr, Nathan E. Cook, Nathan E. Cook, Nathan E. Cook, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson, Grant L. Iverson   +9 more
doaj   +1 more source