Results 241 to 250 of about 114,486 (309)

The Role of HUWE1 on Mouse Neural Cell Proliferation and Zebrafish Neurodevelopment

Medicine Bulletin, EarlyView.
ABSTRACT The HECT, UBA, and WWE domain‐containing E3 ubiquitin protein ligase 1 (HUWE1) gene is located on the X chromosome and has been implicated in neurodevelopmental disorders. However, the mechanisms by which HUWE1 dosage affects nervous system development remain poorly understood. In this study, we demonstrate that HUWE1 overexpression suppresses
Haojuan Wu, Gan Shen, Xueguang Zhang, Xiang Wang, Tiechao Ruan, Chuan Jiang, Yunchuan Tian, Xinyao Tang, Jun Ma, Wenming Xu, Ying Shen   +10 more
wiley   +1 more source

Intrahepatic cholestasis of pregnancy and offspring neurodevelopment: bile acid-mediated mechanisms and long-term neurodevelopmental outcomes. [PDF]

Arch Gynecol Obstet
Dai S, Zhao H, Xie Y, Chen Q, Chen Q, Li Y, Shan D, Tan X, Hu Y.   +8 more
europepmc   +1 more source

Psychiatric Comorbidity, Tic Severity and Quality of Life in Adults with Tourette's Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Psychiatric comorbidities are common in adults with Tourette's Syndrome (TS), and appear to influence both tic severity and quality of life (QOL). Objective To assess the association between psychiatric comorbidities, tic severity and QOL in TS.
Andreas Hartmann, Christelle Nilles, Yulia Worbe, Davide Martino, Naoual Serari, Catherine Deans, Isabella Davenport, Julian Fletcher, Emmanuel Roze, Tamara Pringsheim   +9 more
wiley   +1 more source

Association between thyroid dysfunction during pregnancy and neonatal neurodevelopmental outcomes. [PDF]

Front Pediatr
Kong Y, An X.
europepmc   +1 more source

Natural Killer Subset Changes and Vascular Endothelial Growth Factor‐A Plasma Profile in Progressive Supranuclear Palsy: The NKscape Study

Movement Disorders, EarlyView.
Abstract Background Emerging evidence implicates neuroinflammation in progressive supranuclear palsy (PSP) pathophysiology, with elevated cyto‐chemokines suggesting natural killer (NK) cell involvement. Methods We characterized peripheral NK in PSP (N = 11) versus Parkinson's disease (PD, N = 10) and healthy controls (HC, N = 8) at both ...
Marina Picillo, Cristina Basile, Francesco Montella, Valentina Lopardo, Mariangela Orlando, Roberta Tarallo, Domenico Palumbo, Viola Melone, Maria Francesca Tepedino, Paolo Barone, Annibale Alessandro Puca, Elena Ciaglia   +11 more
wiley   +1 more source

Socioeconomic and nutritional determinants outweigh gut microbiota influence on neurodevelopment in young children from Antananarivo, Madagascar. [PDF]

Sci Rep
Tamarelle J, Doria MV, Rambolamanana V, Rajaonarivo T, Ferreira AS, Rakotondrainipiana M, Randremanana RV, Sansonetti P, Vonaesch P, Afribiota investigators.   +9 more
europepmc   +1 more source

MiR-181a, IL-6, and TNF-α: Biomarkers for Diagnosis and Long-Term Neurodevelopmental Prognosis in Neonatal Sepsis. [PDF]

Infect Drug Resist
Shen J, Yu M, Zhu S, Xue M.
europepmc   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Maternal internalizing symptoms as a mechanism linking pre- and postnatal COVID-19 pandemic exposure with preschool-aged children's neurodevelopment. [PDF]

Arch Womens Ment Health
Finegold KE, Knight JA, Hung RJ, Dennis CL, Shah PS, Wong J, Bertoni K, Levitan RD, Jenkins JM, Matthews SG, Wade M.   +10 more
europepmc   +1 more source