This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez +28 more
wiley +1 more source
Target cells of human adenovirus type 12 in subtentorial brain tissue of newborn mice. I. Cyto-histomorphologic and immunofluorescent microscopic studies In vivo [PDF]
Human adenovirus type 12 (Ad 12) was inoculated through subtentorial route into inbred newborn mice (C3H/BifB/Ki), and sequential changes of the brain and tumor induction were examined by histological and immunofluorescent methods.
Athanasiou, T +9 more
core +1 more source
A Population‐Based Assessment of Cancer Risk in Children With VACTERL
ABSTRACT Cancer risk in children with VACTERL, a nonrandom co‐occurrence of ≥ 3 defects (vertebral, anal, cardiac, tracheoesophogeal fistula, renal, and limb), remains unclear. We evaluated this association in a population‐based study. We analyzed data from the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Study, a US registry linkage ...
Ji Yun Tark +15 more
wiley +1 more source
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd +3 more
wiley +1 more source
Pluripotent Stem Cell-Derived Teratoma presents an embryonic neoplastic niche for in vivo studies of Neuroectodermal Childhood Tumors [PDF]
Therapy-resistance and relapse remain problematic in many cancer patients, despite the advancement in anti-cancer therapies. There is a constant need of developing new anti-cancer drugs to combat tumors keeping in mind also the increasing incidence
Jamil, Seema
core +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Primitive Neuroectodermal Tumor of the Kidney in a 22-Year-Old Male: A Rare Entity
Primitive neuroectodermal tumors of the kidney are rare tumors representing about 1% of all sarcomas. Extraskeletal primitive neuroectodermal tumors may be found in the genitourinary tract, the testes, ovaries, uterus, or pancreas.
Veena Gupta +3 more
doaj
A Case of Long-term Survival in a Patient with Primary Primitive Neuroectodermal Tumor of the Lung [PDF]
Primitive neuroectodermal tumor (PNET) arising primarily in the lung is an extremely rare and aggressive malignancy with poor chances of patient survival.
Lae Hyung Kang +5 more
doaj +1 more source
Diffuse intrinsic pontine glioma biopsy: A single institution experience [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109626/1/pbc25224 ...
Altinok, Deniz +6 more
core +1 more source
Primary Malignant Pulmonary Glomus Tumor: A Case Report and Literature Review
We report a case of primary malignant pulmonary glomus tumor. A mass in the upper lobe of the right lung, with multiple speckled calcifications. The enhanced scan showed uneven enhancement in the arterial phase and progressive enhancement in the venous phase. ABSTRACT Malignant glomus tumors originating from the lungs are relatively rare.
Shishi Luo +4 more
wiley +1 more source

