Results 61 to 70 of about 16,472 (181)
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez +28 more
wiley +1 more source
Melanotic Neuroectodermal Tumor of Infancy
A three-months-old infant was brought to the Department of Pedodontics and Preventive Dentistry, Maulana Azad Institute of Dental Sciences, Delhi by his parents with chief complaint of swelling in upper front gums since 20 days. The onset of swelling was insidious and gradually increased in size. The delivery of child was normal and medical history was
Mridula Goswami +2 more
openaire +3 more sources
ABSTRACT Background Concomitant medications (CMs) influence outcomes in patients receiving immune checkpoint inhibitors (ICIs), but their impact in sarcoma remains undefined. We assessed the association between CM use and ICI outcomes in patients with advanced or metastatic sarcoma. Methods This pooled analysis included patients from seven investigator‐
Adel Shahnam +16 more
wiley +1 more source
The embryonal tumor with abundant neuropil and true rosettes (ETANTR) is an extremely rare variant of the primitive neuroectodermal tumor (PNET). About 80 cases have been reported since its first description in the literature, in 2000.
Cleciton Braga Tavares +4 more
doaj +1 more source
ABSTRACT Postauricular granular cell tumors mimic parotid malignancies. Their resection disrupts fragile local microcirculation due to inherently thin skin and limited subcutaneous buffer, triggering ischemic necrosis and MRSE infection. Clinicians must prioritize functional tissue preservation and vigilant wound care to prevent these severe ...
Haotong Yuan +4 more
wiley +1 more source
Chemotherapy For Medulloblastoma
The efficacy of adjuvant chemotherapy for patients with poor-risk medulloblastoma/primitive neuroectodermal tumors (MB/PNET) has been studied at the Children’s Hospital of Philadelphia, University of Pennsylvania, PA.
J Gordon Millichap
doaj +1 more source
Generation and Characterization of Twist1 Acetyl‐Mimic and Acetyl‐Deficient Mouse Models
ABSTRACT TWIST1 encodes a highly conserved basic helix–loop–helix transcription factor essential for embryonic development from Drosophila to humans. TWIST1 activity is regulated by post‐translational modifications, including phosphorylation during development and cancer metastasis. Recent cancer studies identified acetylation of lysines K73 and K76 as
Mary Elmeniawi +6 more
wiley +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
FNA diagnosis of CD99 positive neuroblastoma: A diagnostic dilemma
Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap.
Gagandeep Kaur +2 more
doaj +1 more source

