Results 171 to 180 of about 278,007 (254)

AI-powered histopathology classifiers identify transcriptomic biomarkers associated with cell cycle regulation and increased mitotic activity in poorly differentiated neuroendocrine carcinoma. [PDF]

Hum Genomics
Khumpan T, Chewe K, Vijayvergia N, Eleam E, Quiñones-Romero JN, Peri S, Yulan G, Engstrom PF, Cai KQ, Pei J, Alekbaeva GD, Campbell KS, Whetstine JR, Astsaturov I, Lee H.   +14 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Clinical Characteristics and Survival Outcomes of a Clinically Defined Treatment-Emergent Neuroendocrine/Aggressive-Variant Prostate Cancer Phenotype: A Retrospective Study. [PDF]

Medicina (Kaunas)
Taban H, Aksoy S, Güven DC, Aktaş BY, Yılmaz F, Aslan F, Erman M.   +6 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Lineage plasticity and immune invisibility in primary SCLC and LUAD-to-SCLC transformation: antigen presentation loss and therapeutic redirection. [PDF]

Front Immunol
Xu H, Li B, Yang J, Tang X.
europepmc   +1 more source

Microvascular Abnormalities in Adolescents With Anorexia Nervosa: Nailfold Video Capillaroscopic Evidence at Acute and Remission States

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Chronic malnutrition, hypothermia, and hormonal imbalance in anorexia nervosa (AN) may impair capillary structure and perfusion. This study aimed to describe the nailfold videocapillaroscopy (NVC) findings in adolescents with AN and atypical AN (AAN), to assess their association with Raynaud's phenomenon (RP), and evaluate ...
Muserref Kasap‐Cuceoglu, Melis Pehlivanturk‐Kizilkan, Erdal Sag, Seher Sener, Zeynep Balik, Sinem Akgul, Orhan Derman, Yelda Bilginer, Nuray Kanbur, Seza Özen   +9 more
wiley   +1 more source

Case Report: Neuroendocrine-low POU2F3-positive small cell lung cancer presenting as a diagnostically unstable thoracic malignancy. [PDF]

Front Oncol
Ma Y, Chen W, Guo F, Han S.
europepmc   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

CDR-Informed Graph Neural Network for Plasma Metabolomics in Lung Cancer and Pulmonary Neuroendocrine Neoplasms. [PDF]

Int J Mol Sci
Himdiat E, Haince JF, Bux RA, Huang G, Tappia PS, Ramjiawan B, Vaida M.   +6 more
europepmc   +1 more source

Screening and identification of novel peptides stimulating GLP‐1 secretion from plant proteins after simulated gastrointestinal digestion

Food Biomacromolecules, EarlyView.
Effects of digestive products of quinoa, oat, barley, and mungbean proteins on GLP‐1 secretion are investigated using STC‐1 cell and animal experiments, and novel GLP‐1 secretion‐stimulating peptides are successfully identified by column chromatography and LC–MS/MS.
Hongdong Song, Shaoxia Ren, Qiuyun Fu, Lei Xue, Kai Huang, Hongwei Cao, Zetang Zhang, Junhu Li, Xiao Guan   +8 more
wiley   +1 more source