Hypervision Proton Surgery: The Future Direction of Proton Therapy
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
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Gastric neuroendocrine tumors: a comprehensive analysis of clinicopathological characteristics and survival outcomes from a reference center. [PDF]
Ribeiro MB +7 more
europepmc +1 more source
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
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Enhancing Diagnostic Pathways for Bronchopulmonary Neuroendocrine Tumors: Assessment of the South Wales Neuroendocrine Tumor Service Transformation. [PDF]
Imtiaz A +7 more
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Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi +13 more
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Bilateral multifocal renal neuroendocrine carcinoma with synchronous pancreatic neuroendocrine carcinoma and adrenal lesion. [PDF]
Huynh QH +4 more
europepmc +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
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Expression and Diagnostic Significance of Clinical Routine VMAT2 Immunostaining in Neuroendocrine Neoplasia: A Study of Institutional Cases. [PDF]
Ankers Z, Hellgren LS, Juhlin CC.
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ABSTRACT Background and Aims Contrast‐enhanced endoscopic ultrasonography (CE‐EUS) provides clearer visualization of wall layer structures in gallbladder nodules than B‐mode EUS. This study aimed to compare the diagnostic performance of B‐mode EUS and CE‐EUS in differentiating benign from malignant gallbladder lesions.
Kensaku Yoshida +7 more
wiley +1 more source
Integrated transcriptomic and proteomic validation identifies SLC35D3 as a tumor-selective surface antigen for colorectal and neuroendocrine carcinomas. [PDF]
Someya S +4 more
europepmc +1 more source

