Results 111 to 120 of about 99,632 (265)

A Prediction Model for One‐Year Disability Risk Among Community‐Dwelling Older Adults in China: Integrating Physical, Metabolic, and Psychosocial Factors

open access: yesHealth Care Science, EarlyView.
Based on a prospective cohort of 1003 older adults, we developed and validated a practical disability prediction model integrating physical, metabolic, and psychosocial factors (AUC = 0.716), presented via a user‐friendly nomogram for community use. ABSTRACT Background Disability in older adults, characterized by progressive limitations in performing ...
Yanjun Ma   +8 more
wiley   +1 more source

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder   +11 more
wiley   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange   +16 more
wiley   +1 more source

Case Report: Large Cell Neuroendocrine Carcinoma of the Palatine Tonsil in a 76‐Year‐Old Patient

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Large cell neuroendocrine carcinoma (LCNEC) of the palatine tonsil is an extremely rare malignancy characterized by an aggressive clinical course and poor prognosis. Its nonspecific presentation often delays diagnosis. Methods We present the case of a 76‐year‐old female patient admitted to the Emergency Department with throat ...
Agnieszka Bugaj   +5 more
wiley   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

open access: yesInternational Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki   +12 more
wiley   +1 more source

CD8+ T Lymphocytes in Pituitary Neuroendocrine Tumors: Friend or Foe? [PDF]

open access: yesCells
Nastase VN   +9 more
europepmc   +1 more source

Transcriptome‐Based Classification of Resected Pancreatic Ductal Adenocarcinoma Enhances Prognostic Modelling Accuracy of Overall Survival Following Adjuvant Treatment

open access: yesInternational Journal of Cancer, EarlyView.
Outcomes after resection of pancreatic ductal adenocarcinoma remain highly variable, and existing prognostic models lack sufficient accuracy. Here, the authors aimed to improve survival prediction by integrating transcriptome‐based subtyping into a validated clinical model and applying it to a multicenter real‐world cohort of fresh‐frozen resection ...
Marjolein F. Lansbergen   +20 more
wiley   +1 more source

Derivation and Validation of a Predictive Model for Advanced Colorectal Neoplasia Among Average‐Risk Adults in China

open access: yesInternational Journal of Cancer, EarlyView.
Efficient pre‐colonoscopy risk stratification tools are needed, especially in China. Using multicenter colorectal cancer screening data from Shandong Province, the authors developed and validated a risk prediction model for advanced colorectal neoplasia in asymptomatic individuals using sociodemographic characteristics, lifestyle factors, and medical ...
Yan Liu   +6 more
wiley   +1 more source

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