Results 71 to 80 of about 3,000,774 (406)

Lanreotide in metastatic enteropancreatic neuroendocrine tumors.

New England Journal of Medicine, 2014
BACKGROUND Somatostatin analogues are commonly used to treat symptoms associated with hormone hypersecretion in neuroendocrine tumors; however, data on their antitumor effects are limited.
Martyn Caplin, Marianne Pavel, J. Ćwikła, Alexandria T Phan, Markus Raderer, E. Sedláčková, Guillaume Cadiot, E. Wolin, Jaume Capdevila, Lucy Wall, Guido Rindi, A. Langley, Séverine Martinez, J. Blumberg, P. Ruszniewski   +14 more
semanticscholar   +1 more source

What is New in 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing.

Archives of Pathology & Laboratory Medicine, 2020
CONTEXT.— The 5th edition of the World Health Organization classification of digestive system tumors discusses several advancements and developments in understanding the etiology, pathogenesis, and diagnosis of several digestive tract tumors. OBJECTIVE.
N. Assarzadegan, E. Montgomery
semanticscholar   +1 more source

Cornelia de Lange syndrome and cancer: An open question

, 2023
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 292-295, January 2023.
Maria M. Pallotta, Maddalena Di Nardo, Raoul C. M. Hennekam, Frank J. Kaiser, Ilaria Parenti, Juan Pié, Feliciano J. Ramos, Antonie D. Kline, Antonio Musio   +8 more
wiley   +1 more source

Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]

, 2017
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen, De Man, Marc, Geboes, Karen, Hoorens, Anne, Troisi, Roberto, Van Vlierberghe, Hans   +5 more
core   +2 more sources

One‐year COVID‐19 outcomes on the oncology care patient pathway: Results of a French descriptive, cross‐sectional comprehensive study (ONCOCARE‐COV)

Cancer Medicine, Volume 11, Issue 24, Page 4865-4879, December 2022., 2022
Key steps in the oncology care pathway activity were retrospectively analyzed and compared in this comprehensive and cross‐sectional study, between the different time settings in the COVID‐19 pandemic. Oncology care were heavily disrupted during the first and second COVID‐19 outbreak waves with decrease in screening and diagnosis activity as well as an
Léonard Laurent, Mathias Brugel, Claire Carlier, Florentin Clere, Aurélie Bertrand, Damien Botsen, Camille Boulagnon‐Rombi, Véronique Dalstein, Adeline Debreuve‐Theresette, Sophie Deguelte, Christian Garbar, Rachid Mahmoudi, Antonin Marechal, David Morland, Jean‐Baptiste Rey, Claire Schvartz, Catherine Vallet, Yacine Merrouche, Florian Slimano, Olivier Bouché   +19 more
wiley   +1 more source

A Retrospective Analysis of the Correlation between Functional Imaging and Clinical Outcomes in Grade 3 Neuroendocrine Tumors (NETs G3)

Diagnostics, 2021
Grade 3 (G3) neuroendocrine tumors (NETs) are a novel category among digestive neuroendocrine neoplasms, characterized by Ki-67 >20% and a well-differentiated morphology, presenting high intra-tumor heterogeneity.
Alice Laffi, Marzia Colandrea, Giuseppe Buonsanti, Samuele Frassoni, Vincenzo Bagnardi, Francesca Spada, Eleonora Pisa, Massimo Barberis, Manila Rubino, Chiara Maria Grana, Francesco Ceci, Nicola Fazio   +11 more
doaj   +1 more source

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Nature Network Boston, 2019
Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are therefore considered ‘non-functional’1–3. As clinical behaviors vary widely and distant metastases are eventually lethal2,4, biological classifications might guide ...
P. Cejas, Y. Drier, K. Dreijerink, L. Brosens, V. Deshpande, C. Epstein, E. Conemans, F. Morsink, M. Graham, G. Valk, M. Vriens, C. F. Castillo, C. Ferrone, T. Adar, M. Bowden, Holly J. Whitton, Annacarolina da Silva, Alba Font-Tello, Henry W. Long, Elizabeth Gaskell, N. Shoresh, C. Heaphy, E. Sicinska, M. Kulke, D. Chung, B. Bernstein, R. Shivdasani   +26 more
semanticscholar   +1 more source

Clinical characteristics, prognostic factors, and survival trends in esophageal neuroendocrine carcinomas: A population‐based study

Cancer Medicine, Volume 11, Issue 24, Page 4935-4945, December 2022., 2022
Esophageal neuroendocrine carcinoma (ENEC) is an extremely rare type of malignancy. This study collected information of 283 ENEC patients diagnosed pathologically from 2010‐2018. Multivariate survival analysis showed that ENEC located at the middle third of esophagus (p = 0.013), “Brain metastasis” (p = 0.019), and “Liver metastasis” (p < 0.001) were ...
Chuyan Chen, Haiyi Hu, Zhibo Zheng, Yi Yang, Wei Chen, Xinwei Qiao, Peng Li, Shutian Zhang   +7 more
wiley   +1 more source

MEN1 Deficiency‐Driven Activation of the β‐Catenin‐MGMT Axis Promotes Pancreatic Neuroendocrine Tumor Growth and Confers Temozolomide Resistance

Advanced Science
O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ).
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji   +16 more
doaj   +1 more source

An Intraoperative $β^-$ Detecting Probe For Radio-Guided Surgery in Tumour Resection [PDF]

, 2015
The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for brain tumours.
arxiv   +1 more source