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Imaging of pancreatic neuroendocrine tumors: recent advances, current status, and controversies
Introduction: Recently, there have been a number of advances in imaging pancreatic neuroendocrine tumors (panNETs), as well as other neuroendocrine tumors (NETs), which have had a profound effect on the management and treatment of these patients, but in ...
Lingaku Lee, Tetsuhide Ito, R. Jensen
semanticscholar +1 more source
Phosphatidylinositol 3-kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities. [PDF]
BackgroundThe phosphatidylinositol 3-kinase (PI3K) pathway is frequently altered in cancer. This report describes the landscape of PI3K alterations in solid tumors as well as co-alterations serving as potential resistance/attenuation mechanisms ...
Albacker, Lee+6 more
core +1 more source
Management of Gastrointestinal Neuroendocrine Tumors
Neuroendocrine neoplasms (NENs) are derived from neuroendocrine cell system and can have benign or malignant characteristics. They are rare tumors, but have been increasing in incidence over the past 40 years.
Rongzhi Wang+5 more
semanticscholar +1 more source
IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]
Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C.+9 more
core +1 more source
. Neuroendocrine tumors are rare tumors of the gastrointestinal tract. The differential diagnosis of neuroendocrine tumors remains poorly understood. Objective.
V Yakovenko
doaj +1 more source
Role of magnetic resonance imaging in the detection and characterization of solid pancreatic nodules: an update [PDF]
Pancreatic ductal adenocarcinoma is the most common malignant tumor of the pancreas. The remaining pancreatic tumors are a diverse group of pancreatic neoplasms that comprises cystic pancreatic neoplasms, endocrine tumors and other uncommon pancreatic ...
Ansari, Najwa Al+5 more
core +1 more source
Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner. [PDF]
Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor progression and resistance to androgen signaling deprivation therapy (ADT).
Agarwal, Priyanka+14 more
core +1 more source
Pancreatic tumors imaging: an update [PDF]
Currently, ultrasound (US), computed tomography (CT) and Magnetic Resonance imaging (MRI) represent the mainstay in the evaluation of pancreatic solid and cystic tumors affecting pancreas in 80-85% and 10-15% of the cases respectively. Integration of US,
Baccari, Paolo+8 more
core +1 more source
AIM To review literature on efficacy and safety of octreotide-long-acting repeatable (LAR) used at doses higher than the Food and Drug Administration (FDA)-approved 30 mg/mo for treatment of neuroendocrine tumors (NETs).
M. Broder+4 more
semanticscholar +1 more source
Neuroendocrine cells are widespread throughout the body and can give rise of neuroendocrine tumors due to abnormal growth of the chromaffin cells. Neuroendocrine tumors divide into many subtypes based on tumor grade (Ki-67 index and mitotic count) and ...
Kishore Kumar+6 more
doaj +1 more source