Results 121 to 130 of about 54,369 (243)
Regulation of ER Stress‐Associated Gene Expression by Lifeguard in Human Breast Cancer Cells
ABSTRACT Background Despite significant advances in breast cancer therapy, resistance to apoptosis remains a major obstacle to successful treatment. Lifeguard (LFG), an antiapoptotic membrane protein, has been implicated in breast cancer progression; however, its role in endoplasmic reticulum (ER) stress‐associated molecular responses and apoptosis ...
Inga Nebel +5 more
wiley +1 more source
La neurofibromatosis (NF) es un trastorno hereditario caracterizado por la formación de neurofibromas (tumores que involucran al tejido nervioso) en la piel, tejido subcutáneo, nervios craneales y los nervios de la base de la columna vertebral1,2 ...
Teresa de los A. Casanova Rodríguez +2 more
doaj
Gigantic neurofibromatosis of the orbit.
A case of gigantic orbital neurofibromatosis (2,500 gm) is presented. It is believed to be the largest such tumor reported since the famous elephantiasis neurofibromatosis pictured in von Bruns' Chirurgischer Atlas in ...
Gumener R, Pittet B, Montandon D
core +1 more source
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source
Abstract Beyond physical challenges, cancer can cause psychological and cognitive challenges for patients, caregivers, and family members. Digital health interventions show promise in addressing these issues. However, evidence on their applicability in daily cancer care is limited. The objective of this systematic review is to evaluate the internal and
Melissa Heifez +16 more
wiley +1 more source
Extensive retinal microvascular malformation involving both small and large retinal vessels. (Ref: BJO 2002:86, p282-284). Anatomy: Retina. Pathology: Retinal microvascular malformations. Disease/Diagnosis: Neurofibromatosis type 1.
William F. Hoyt, MD
core
Familial Spinal Neurofibromatosis
The clinical features and genetic linkage analysis of two pedigrees with familial spinal neurofibromatosis (NF) are described from the Divisions of Neurology and Medical Genetics, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA; the
J Gordon Millichap
core +1 more source
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart +11 more
wiley +1 more source

