Results 51 to 60 of about 54,369 (243)
Healthcare utilization patterns and costs related to neurofibromatosis 1 in Ontario, Canada
Orphanet Journal of Rare DiseasesBackground and objectives Neurofibromatosis type 1 (NF1) is a multisystemic disease, characterized by cutaneous manifestations and peripheral nerve sheath tumors.
Ajith Sivadasan +6 more
doaj +1 more source
An innovative resection of giant neurofibromas
Chinese Journal of Plastic and Reconstructive SurgeryBackground: Plexiform neurofibromas (PNF) are highly vascular tumors with the potential for significant growth. Surgical removal of giant PNF is often challenging because of intraoperative hemorrhage.
Zhichao Wang +7 more
doaj +1 more source
Extensive Plexiform Neurofibroma Presenting as Clitoromegaly in Neurofibromatosis Type 1
Journal of Behçet Uz Children's Hospital, 2021 Neurofibromatosis type 1 (NF1) is an autosomal-dominant disorder with multisystem involvement. Genitourinary involvement of neurofibromatosis type 1 is rare condition and involvement of plexiform neurofibroma can cause painful clitoromegaly. A 9-year-old
Özlem Nalbantoğlu +4 more
doaj +1 more source
Intrascrotal Solitary Neurofibroma [PDF]
Journal of Clinical and Diagnostic Research, 2020 A BSTRACT Solitary Neurofibroma of the scrotum is a rare benign tumour, particularly when it is not associated with neurofibromatosis Type I, hence, less number of cases have been reported in the English literature.
Abhishek Gupta, Suhas N Jajoo
doaj +1 more source
Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
Indian Journal of Dentistry, 2014 Segmental neurofibromatosis is a rare disorder, characterized by neurofibromas or cafι-au-lait macules limited to one region of the body. Its occurrence on the face is extremely rare and only few cases of segmental neurofibromatosis over the face have been described so far.
Galhotra, Virat +3 more
openaire +5 more sources
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
Abordaje clínico de variantes fenotípicas en neurofibromatosis de tipo 1 [PDF]
, 2019 Neurofibromatosis type 1 is an autosomal dominant disorder, with multisystemic affectation and high phenotypic variation, caused by NF1 mutation in the locus 17 q11.2 that codes for neurofibromin.The estimated prevalence of people affected by this ...
López, Jairo Enrique +1 more
core
European Journal of Human Genetics, 2006 Neurofibromatosis 1 predisposes affected individuals to the development of benign and malignant tumours that are frequently disfiguring and difficult to manage. However, advances in molecular biology and the development of mouse models have facilitated our understanding of disease pathogenesis.
openaire +2 more sources
, 2011 Neurofibromatosis 1 and 2 have historically been grouped together. However they represent two distinct diseases separated both genetically and clinically.
George Tharakan
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