Results 91 to 100 of about 39,192 (197)

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

open access: yesClinical Anatomy, Volume 39, Issue 8, Page 965-979, November 2026.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Genetic Spectrum of Non‐PTPN11 Variants in Noonan Syndrome and Related RASopathies: Findings From a Russian Cohort

open access: yesClinical Genetics, Volume 110, Issue 5, Page 527-537, November 2026.
Noonan syndrome and related conditions are caused by variants in multiple genes. We analyzed 456 Russian patients using a 23‐gene panel and found disease‐causing variants in non‐PTPN11 genes in 85 cases. NF1, SOS1, BRAF, and SHOC2 explained half of these diagnoses.
Anna Orlova   +5 more
wiley   +1 more source

Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea

open access: yesCell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco   +6 more
wiley   +1 more source

Australian Guideline for the Identification and Management of Hypertension in Children and Adolescents

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
N. G. Larkins   +28 more
wiley   +1 more source

Intranodal Epithelioid Schwannoma in an Intraparotid Lymph Node: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT An epithelioid schwannoma arising within an intraparotid lymph node is a rare benign lesion that may mimic metastatic melanoma, metastatic carcinoma, or a primary salivary gland neoplasm. Recognizing the intranodal architecture and integrating morphology with an appropriate immunohistochemical panel are essential to avoid misclassification and
Maryam Vajihinejad   +3 more
wiley   +1 more source

Neurofibromatosis type 1

open access: yesMuller Journal of Medical Sciences and Research, 2013
P Chaitra, M Ramesh Bhat
doaj   +1 more source

Decreased PP2A expression and activity represent a therapeutic target for plexiform neurofibroma

open access: yesActa Neuropathologica Communications
In neurofibromatosis type 1 (NF1), loss-of-function mutations in the NF1 gene increase activation of the RAS–MEK–ERK signaling cascade, driving tumorigenesis. MEK inhibitors (MEKi) inhibit tumor growth and significantly shrink nerve tumors (neurofibromas)
Minghui Yue   +11 more
doaj   +1 more source

Solitary Nodule in the Hard Palate

open access: yes
Oral Diseases, EarlyView.
Sara Lia Gonçalves de Lima   +6 more
wiley   +1 more source

Regulation of ER Stress‐Associated Gene Expression by Lifeguard in Human Breast Cancer Cells

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Despite significant advances in breast cancer therapy, resistance to apoptosis remains a major obstacle to successful treatment. Lifeguard (LFG), an antiapoptotic membrane protein, has been implicated in breast cancer progression; however, its role in endoplasmic reticulum (ER) stress‐associated molecular responses and apoptosis ...
Inga Nebel   +5 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

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