Results 131 to 140 of about 34,784,083 (239)
Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley +1 more source
Noonan syndrome and related conditions are caused by variants in multiple genes. We analyzed 456 Russian patients using a 23‐gene panel and found disease‐causing variants in non‐PTPN11 genes in 85 cases. NF1, SOS1, BRAF, and SHOC2 explained half of these diagnoses.
Anna Orlova +5 more
wiley +1 more source
Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco +6 more
wiley +1 more source
ISCHEMIC RETINOPATHY IN NEUROFIBROMATOSIS TYPE 1
PURPOSE: To describe a patient with severe ischemic retinopathy and maculopathy in the context of neurofibromatosis Type 1. METHODS: Case report illustrated with multimodal clinical imaging.
Freund, K. B. +4 more
core +1 more source
Intranodal Epithelioid Schwannoma in an Intraparotid Lymph Node: A Case Report and Literature Review
ABSTRACT An epithelioid schwannoma arising within an intraparotid lymph node is a rare benign lesion that may mimic metastatic melanoma, metastatic carcinoma, or a primary salivary gland neoplasm. Recognizing the intranodal architecture and integrating morphology with an appropriate immunohistochemical panel are essential to avoid misclassification and
Maryam Vajihinejad +3 more
wiley +1 more source
Solitary Nodule in the Hard Palate
Oral Diseases, EarlyView.
Sara Lia Gonçalves de Lima +6 more
wiley +1 more source
Regulation of ER Stress‐Associated Gene Expression by Lifeguard in Human Breast Cancer Cells
ABSTRACT Background Despite significant advances in breast cancer therapy, resistance to apoptosis remains a major obstacle to successful treatment. Lifeguard (LFG), an antiapoptotic membrane protein, has been implicated in breast cancer progression; however, its role in endoplasmic reticulum (ER) stress‐associated molecular responses and apoptosis ...
Inga Nebel +5 more
wiley +1 more source
Bilateral Giant Plexiform Neurofibromas In Neurofibromatosis Type 1
A single plexiform neurofibroma or two of any type are considered diagnostic of neurofibromatosis type 1 (NF). Plexiform neurofibromas are congenital and pathognomonic for NF-1.
Jeevankumar B +2 more
core
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source

