Results 91 to 100 of about 25,034,870 (238)
an international symposium held in Pavia on July 4th, 2014 [PDF]
New progresses into the molecular and cellular mechanisms of autism spectrum disorders (ASDs) have been discussed in 1 day international symposium held in Pavia (Italy) on July 4th, 2014 entitled “synapses as therapeutic targets for autism spectrum ...
Ben-Ari, Yehezkel +8 more
core +1 more source
Biphasic Hyalinizing Psammomatous Renal Cell Carcinoma (BHP RCC)
Supplemental Digital Content is available in the text. We report 8 cases of a distinctive, previously undescribed renal cell carcinoma associated with somatic mutations in the neurofibromin 2 (NF2) gene.
P. Argani +10 more
semanticscholar +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Background Chaka sheep, named after Chaka Salt Lake, are adapted to a harsh, highly saline environment. They are known for their high-grade meat quality and are a valuable genetic resource in China.
Jie Cheng +11 more
doaj +1 more source
Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival [PDF]
As a critical regulator of cell growth, the mechanistic target of rapamycin (mTOR) protein operates as part of two molecularly and functionally distinct complexes. Herein, we demonstrate that mTOR complex molecular composition varies in different somatic
Gutmann, David H, Smithson, Laura J
core +2 more sources
Details of the “GEF only” and “GAP only” model. (PDF 174 kb)
Hennig, Anne +8 more
openaire +1 more source
Metabolic scavenging by cancer cells: when the going gets tough, the tough keep eating [PDF]
Cancer is fundamentally a disease of uncontrolled cell proliferation. Tumour metabolism has emerged as an exciting new discipline studying how cancer cells obtain the necessary energy and cellular ‘building blocks’ to sustain growth.
Bulusu, Vinay +2 more
core +2 more sources
Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with a 5‐year survival rate of approximately 50%, secondary to their metastatic potential and resistance to therapy. MPNSTs can arise sporadically, as a late toxicity from therapeutic radiotherapy, or in patients with neurofibromatosis type 1 (NF1).
Rachel E. Aubrey +7 more
wiley +1 more source
Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma [PDF]
Low-grade brain tumors (pilocytic astrocytomas) arising in the neurofibromatosis type 1 (NF1) inherited cancer predisposition syndrome are hypothesized to result from a combination of germline and acquired somatic NF1 tumor suppressor gene mutations ...
Demeter, Ryan +14 more
core +2 more sources
Dynamic causal modelling of working memory fMRI in individuals with Neurofibromatosis Type 1 (NF1) revealed altered frontoparietal connectivity. NF1 participants showed increased endogenous self‐connectivity in left dlPFC and IPG. During working memory, NF1 participants showed increased self‐connectivity in left vlPFC but decreased self‐connectivity in
Marta C. Litwińczuk +3 more
wiley +1 more source

