Results 191 to 200 of about 25,034,870 (238)

A case of neurofibromatosis type 1 with neurofibromatosis type 1-related and neurofibromatosis type 1-unrelated tumors: a case report. [PDF]

J Med Case Rep
Hartung TI, Karimi Q, Kluwe L, Farschtschi SC.   +3 more
europepmc   +1 more source

Loss of Schwann cell's normal rhythmic core clock gene expression and gain of rhythmic expression of oncogenic driver genes in malignant NF1-associated peripheral nerve sheath tumor. [PDF]

Mol Cell Oncol
Leisz S, Pelligrino A, Fritzsche S, Wiegers M, Wösle M, Linke C, Lohse S, Tippner D, Scheller C, Strauss C, Ehrentreich-Förster E, Dehghani F, Sys S, Maronde E, Harder A.   +14 more
europepmc   +1 more source

Neurofibromatosis type 1 with unilateral macrodactyly-like overgrowth: a case report. [PDF]

Case Reports Plast Surg Hand Surg
Klaus L, Hoh M, Beyersdorf B, Ruemmele D, Jallow ASH, Mtaita DG, Dolderer J.   +6 more
europepmc   +1 more source

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Abstract P2057: The Role Of Cardiac Neurofibromin-2 In Chronic Pressure Overload

Circulation Research, 2023
Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers University, Newark, NJ 07103.Neurofibromin 2 (NF2) is a tumor suppressor that can engage the Hippo signaling pathway and modulate cell proliferation and survival.
Satvik Mareedu, Yu Zhang, Wataru Mizushima, Jamie J Francisco, Jin Guan, Zhi Yang, Shinichi Oka, P. Zhai, M. Abdellatif, Dominic P Del Re   +9 more
semanticscholar   +2 more sources

Abstract B19: Neurofibromin 2 regulates metabolism in the heart

Molecular Cancer Research, 2020
Introduction: Neurofibromin 2 (NF2) is a tumor suppressor that can engage the Hippo signaling pathway and modulate cell proliferation and survival. We previously demonstrated that NF2 mediates cardiomyocyte apoptosis and injury caused by acute myocardial
Yu Zhang, Wataru Mizushima, S. Oka, P. Zhai, D. Re   +4 more
semanticscholar   +2 more sources

Abstract 441: Neurofibromin 2 Regulates Metabolism in the Heart

Circulation Research, 2020
Background: Neurofibromin 2 (NF2) is a tumor suppressor and signaling platform that can engage the Hippo pathway to modulate cell proliferation and survival. We previously demonstrated that NF2 mediates injury caused by acute myocardial infarction (MI)
Yu Zhang, Wataru Mizushima, S. Oka, Zhi Yang, P. Zhai, M. Abdellatif, D. Re   +6 more
semanticscholar   +2 more sources

Targeting Neurofibromin 2 (NF2) prevents endothelial dysfunction in obesity: a study in mice and humans

European Heart Journal, 2022
The mechanisms underlying endothelial dysfunction (ED) in obesity are poorly understood. Neurofibromin 2 (NF2) is a scaffold-like protein involved in cell growth and survival. However, its role in the vascular endothelium is unknown.
S. Costantino, S. Mohammed, E. Gorica, S. Ambrosini, A. Akhmedov, A. Virdis, F. Ruschitzka, S. Masi, F. Paneni   +8 more
semanticscholar   +2 more sources

Abstract Tu116: Neurofibromin 2 regulates metabolic gene expression and cardiac responses to pressure overload stress

Circulation Research
Background: Neurofibromin 2 (NF2) is a tumor suppressor that can engage multiple signaling pathways to modulate cell proliferation and survival. We previously demonstrated that NF2 mediates cardiomyocyte apoptosis and cardiac injury caused by acute ...
Yu Zhang, Satvik Mareedu, Wataru Mizushima, Jamie J Francisco, Jin Guan, Zhi Yang, Shinichi Oka, P. Zhai, M. Abdellatif, J. Sadoshima, Dominic P Del Re   +10 more
semanticscholar   +2 more sources