Results 241 to 250 of about 102,686 (380)

Neuronal cell death and axonal degeneration: Neurofilaments as biomarkers. [PDF]

, 2009
Petzold, A
core  

Dysphagia in Multiple System Atrophy Does Not Correlate with Serum Neurofilament Light Chain and Glial Fibrillary Acidic Protein

Movement Disorders, EarlyView.
Martin Klietz, Katharina Pannewitz‐Makaj, Franziska Baacke, Florian Wegner, Matthias Höllerhage, Lea Krey, Lan Ye, Christoph Schrader, Günter U. Höglinger, Tobias Warnecke   +9 more
wiley   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Long‐term effects of a multidomain intervention on cognitive function and metabolic control in older adults with type 2 diabetes and mild cognitive impairment: A 42‐month follow‐up of the J‐MIND‐Diabetes study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto, Takuya Omura, Atsushi Araki, Chie Haneda, Keiko Honda, Minoru Kishi, Toshimasa Takahashi, Kenji Toyoshima, Suguru Tsuume, Kazuaki Uchida, Hisashi Noma, Ayaka Onoyama, Yoko Yokoyama, Mio Shinozaki, Paul K. Crane, Takashi Sakurai, J‐MIND‐Diabetes Study Group   +16 more
wiley   +1 more source

Is it time to target no evident disease activity (NEDA) in multiple sclerosis? [PDF]

, 2015
Banwell, Bermel, Cohen, Cohen, Coles, Coles, Comi, Confavreux, Dobson, Erbayat Altay, Giovannoni, Giovannoni, Giovannoni, Hartung, Havrdova, Kappos, Leray, Levesque, Miller, Rio, Scalfari, Solomon, Sormani, Sormani, Tuohy, Zivadinov   +25 more
core   +1 more source

WONOEP XVII appraisal: The immunopathogenesis of epilepsy

Epilepsia, EarlyView.
Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak, Said Al Maawal, Peravina Thergarajan, Tracie H. L. Tan, Vinod Kumar Mehta, Tamara Baker, David C. Henshall, Aristea S. Galanopoulou, Özlem Akman, Pablo M. Casillas‐Espinosa, Raman Sankar, Laura Librizzi, Adam E. Handel   +12 more
wiley   +1 more source

Exploring Brain and Ventricular Boundary Shift Integral Associations with Beta Amyloid and Neurofilament Light in Alzheimer’s Disease [PDF]

Negin Ashoori, Hamide Nasiri, Sahba Shahbazi, Faezeh Rezaei, Soudabeh Davoudabadi, Farzane Hijroudi, Mohammad Bagher Khosravi, Niloofar Malakouti, Zahra Babaei Aghdam, Masoud Noroozi, Mahsa Mayeli   +10 more
openalex   +1 more source

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

The FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut, Danae Campos‐Melo, Michael J. Strong   +2 more
wiley   +1 more source

Serum neurofilament light in familial Alzheimer disease [PDF]

, 2017
Philip S.J. Weston, Teresa Poole, Natalie S. Ryan, Akshay Gopinathan Nair, Yuying Liang, Kirsty Macpherson, Ronald Druyeh, Ian B. Malone, R. Laila Ahsan, Hugh Pemberton, Jana Klímová, Simon Mead, Kaj Blennow, Martin N. Rossor, Jonathan M. Schott, Henrik Zetterberg, Nick C. Fox   +16 more
openalex   +1 more source

RB1 inactivation in cutaneous carcinomas

Histopathology, EarlyView.
Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv, Antoine Touzé, David Schrama, Serge Guyétant, Mahtab Samimi, Michael T Tetzlaff, Benjamin A Wood, Paul W Harms, Thibault Kervarrec   +8 more
wiley   +1 more source