Results 51 to 60 of about 5,823,340 (161)

Bladder and bowel dysfunction in Down syndrome with neural tube defect: case report and review of the literature

Italian Journal of Pediatrics, 2023
Background Down syndrome is a genetic disorder caused by trisomy of chromosome 21 and characterized by an increased risk of multiorgan involvement. In Down syndrome children, functional constipation and lower urinary tract infections have been described,
Roberta Onesimo, Cristiana Agazzi, Luca Massimi, Valentina Giorgio, Chiara Leoni, Giuseppe Zampino, Claudia Rendeli   +6 more
doaj   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

The concerns of mechanical upper urinary tract obstruction in neurogenic lower urinary tract dysfunction: Beyond augmentation cystoplasty

Frontiers in Surgery, 2023
PurposeTo evaluate the efficacy of augmentation uretero-enterocystoplasty (AUEC), a modified surgical procedure that focuses the mobilization of the ureter and the necessity of ureteroplasty in a series of neurogenic lower urinary tract dysfunction ...
Zhonghan Zhou, Zhonghan Zhou, Zhonghan Zhou, Zhonghan Zhou, Xuesheng Wang, Xuesheng Wang, Xuesheng Wang, Xuesheng Wang, Limin Liao, Limin Liao, Limin Liao, Limin Liao, Limin Liao   +12 more
doaj   +1 more source

Utility of Pelvic Floor Therapy and Behavioral Interventions in the Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Population

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Neurogenic lower urinary tract dysfunction (NLUTD) describes a wide range of symptoms depending on neurologic diagnosis and the resulting bladder and sphincter dysfunction. This narrative review is designed to address the question regarding which NLUTD population benefits most from pelvic floor therapy and behavioral interventions, and ...
Sara M. Lenherr
wiley   +1 more source

Nerve growth factor does not seem to be a biomarker for neurogenic lower urinary tract dysfunction after spinal cord injury. [PDF]

, 2017
AIM To prospectively investigate the association of bladder function with the nerve growth factor (NGF) concentration in the urine of individuals with neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury (SCI).
Stoyanov, Jivko, Pannek, Jürgen, Wöllner, Jens, Krebs, Jörg, Pavlicek, David, David Pavlicek, Jörg Krebs, Jivko Stoyanov, Jens Wöllner, Jürgen Pannek   +9 more
core   +1 more source

Clinical application of intravesical botulinum toxin type A for overactive bladder and interstitial cystitis [PDF]

Investigative and Clinical Urology, 2020
After decades of clinical and basic science research, the clinical application of botulinum toxin A (Botox) in urology has been extended to neurogenic detrusor overactivity (NDO), idiopathic detrusor overactivity, refractory overactive bladder (OAB ...
Jing-Liang Chen , Hann-Chorng Kuo
doaj   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

The history of neuromodulation for lower urinary tract dysfunction: An overview

Continence
Electricity has been used since antiquity for medical purposes, including lower urinary tract dysfunction. The advent of artificially produced electricity, the development of battery technology and better knowledge of lower urinary tract physiology ...
Philip E.V. Van Kerrebroeck, Ubi van den Hombergh   +1 more
doaj   +1 more source

Mirabegron and Intradetrusor Onabotulinumtoxina for Overactive Bladder in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To synthesize the evidence on the efficacy and safety of mirabegron and intradetrusor onabotulinumtoxinA (BoNT‐A) as separate interventions for overactive bladder (OAB) in Parkinson's disease (PD). Methods A systematic review and meta‐analysis with parallel synthesis of two distinct interventions was conducted of randomized and ...
Hussain Arshad, Raiyana Nuha, Shehab Khashaba, David Gillatt, Simon J. G. Lewis   +4 more
wiley   +1 more source

Advancing Personalized Care for Neurogenic Bladder: The Case for Continent Urinary Diversion

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Neurogenic lower urinary tract dysfunction (NLUTD) with a poorly compliant bladder that is refractory to minimally invasive therapies (MIT) represents an “end‐stage” phenotype in which the principal objectives are durable upper urinary tract protection and restoration of continence with acceptable long‐term morbidity.
Francis A. Jefferson, Maude E. Carmel
wiley   +1 more source