Results 31 to 40 of about 5,088 (158)

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Sympathetic Overactivation Drives Neurogenic Alveolar Epithelial Pyroptosis via the PIEZO2‐ER Stress Pathway in Acute Lung Injury Following Intracerebral Hemorrhage

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Following intracerebral hemorrhage, sympathetic overactivation drives acute lung injury via norepinephrine‐induced VPS35 upregulation. VPS35 promotes PIEZO2‐mediated calcium influx and impairs ATP2A2‐dependent ER calcium reuptake, triggering ER stress and NLRP3‐pyroptosis.
Shuai Han   +9 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

Long QT Syndrome Type 5 With Coexisting KCNE1 and RYR2 Variants: A Diagnostic Ambiguity

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Long QT syndrome (LQTS) predisposes to syncope and sudden cardiac death. Type 5 LQTS, linked to KCNE1 variants, is rare. A teenage female presented with recurrent syncope. ECG showed QTc 485 ms. Genetic testing identified KCNE1 and RYR2 variants. Beta‐blockers and ICD prevented events.
Mohammad Hossein Nikoo   +4 more
wiley   +1 more source

A Case of MDMA-Associated Cerebral and Pulmonary Edema Requiring ECMO

open access: yesCase Reports in Critical Care, 2017
A 20-year-old female presented with confusion, generalized tonic-clonic seizures, and severe hyponatremia after ingesting 3,4-methylenedioxymethamphetamine (MDMA). Brain computed tomography (CT) demonstrated cerebral edema.
A. Thakkar   +3 more
doaj   +1 more source

Application of transpulmonary thermodilution monitoring (PiCCO) in patient with neurogenic pulmonary edema and acute obstructive hydrocephalus due to a central neurocytoma: A case report

open access: yesInterdisciplinary Neurosurgery, 2017
Neurogenic pulmonary edema (NPE) is an acute life-threatening complication associated with many forms of central nervous system injury. Its pathophysiology is still debated.
Ryoichi Iwata   +5 more
doaj   +1 more source

How to predict neurogenic pulmonary edema in aneurysmal subarachnoid hemorrhage?: Neurogenic pulmonary edema in aneurysmal SAH [PDF]

open access: yesSerbian Journal of Anesthesia and Intensive Therapy, 2019
Introduction: Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema after sudden raise of intracranial pressure.
Nastasović Tijana   +5 more
doaj  

Seizure-Induced Hemoptysis in a Pediatric Patient

open access: yesCase Reports in Pediatrics, 2022
Hemoptysis can complicate seizures, albeit rarely. This unfamiliar presentation, reported infrequently in adults, can also affect children. This remains a rare clinical entity in pediatrics and we report one such case and its association with sterol ...
Ritika Nangia   +3 more
doaj   +1 more source

Exercise-Induced Pulmonary Edema in a Triathlon

open access: yesCase Reports in Medicine, 2015
Introduction. Family physicians have more opportunities to attend athletic competitions as medical staff at first-aid centers because of the increasing popularity of endurance sports. Case.
Hirotomo Yamanashi   +4 more
doaj   +1 more source

Involvement of nitric oxide pathways in neurogenic pulmonary edema induced by vagotomy

open access: yesClinics, 2011
OBJECTIVE: The objective of this study was to evaluate the involvement of peripheral nitric oxide (NO) in vagotomy-induced pulmonary edema by verifying whether the nitric oxide synthases (NOS), constitutive (cNOS) and inducible (iNOS), participate in ...
Eleonora Blanco   +3 more
doaj   +1 more source

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