Results 141 to 150 of about 515,093 (330)

A Novel Transfer Learning‐Based Hybrid EEG‐fNIRS Brain‐Computer Interface for Intracerebral Hemorrhage Rehabilitation

open access: yesAdvanced Science, EarlyView.
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen   +18 more
wiley   +1 more source

Genetic variation affecting exon skipping contributes to brain structural atrophy in Alzheimer's disease [PDF]

open access: yes, 2018
Genetic variation in cis-regulatory elements related to splicing machinery and splicing regulatory elements (SREs) results in exon skipping and undesired protein products.
Alzheimer’s Disease Neuroimaging Initiative   +8 more
core  

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee   +13 more
wiley   +1 more source

Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu   +9 more
wiley   +1 more source

Neuroimaging of Habit-based vs. Goal-directed behavior in Instrumental Learning [PDF]

open access: yes, 2017
Addiction has been proposed to result from an overreliance on the habit-based and goal-directed controllers of behavior; however, few data exist to simultaneously support both behavioral and neuoranatomical aspects of this theory in humans.
Lawler, Michael Jacob
core   +1 more source

Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

open access: yesAdvanced Science, EarlyView.
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan   +4 more
wiley   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

open access: yesAdvanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy