Results 151 to 160 of about 252,991 (337)

Lentivirus Infection Causes Neuroinflammation and Neuronal Injury in Dorsal Root Ganglia: Pathogenic Effects of STAT-1 and Inducible Nitric Oxide Synthase [PDF]

open access: hybrid, 2005
Yu Zhu   +7 more
openalex   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol   +3 more
wiley   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

Alcohol Abuse Enhances Neuroinflammation and Impairs Immune Responses in an Animal Model of Human Immunodeficiency Virus-1 Encephalitis [PDF]

open access: bronze, 2006
Raghava Potula   +9 more
openalex   +1 more source

The GLP1R Agonist Semaglutide Inhibits Reactive Astrocytes and Enhances the Efficacy of Neural Stem Cell Transplantation Therapy in Parkinson's Disease Mice

open access: yesAdvanced Science, EarlyView.
Compared to transplantation of neural stem cells (NSCs) alone, the combined treatment of NSCs with semaglutide more effectively improves motor dysfunction in Parkinson's disease (PD) mice. This synergistic effect may result from semaglutide's ability to suppress microglial activation, thereby preventing the transformation of resting astrocytes into ...
Dan Song   +6 more
wiley   +1 more source

Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson’s disease [PDF]

open access: green, 2006
R. Lee Mosley   +7 more
openalex   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser   +11 more
wiley   +1 more source

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