Results 161 to 170 of about 135,205 (333)

Positron Emission Tomography Imaging of Neuroinflammation [PDF]

, 2007
Annachiara Cagnin, Michael Kassiou, Steven R. Meikle, Richard B. Banati   +3 more
openalex   +1 more source

Deep‐Learning Model for Central Nervous System Infection Diagnosis and Prognosis Using Label‐Free 3D Immune‐Cell Morphology in the Cerebrospinal Fluid

Advanced Intelligent Systems, EarlyView.
Early diagnosis and prognosis prediction of central nervous system infections are critical. This study introduces a deep‐learning model utilizing cerebrospinal fluid immune‐cell morphology captured via 3D holotomography. The model effectively predicts infection etiology and prognosis, achieving high accuracy.
Bo Kyu Choi, Ho Heon Yang, Jong Hyun Kim, JaeSeong Hong, Kyung Min Kim, Yu Rang Park   +5 more
wiley   +1 more source

Modeling the prion protein-mediated transport of extracellular vesicles on the neuron surface [PDF]

arXiv
Neurodegenerative diseases are among the leading causes of global mortality. They are characterized by the progressive deterioration of specific neuron populations, ultimately leading to cognitive decline and dementia. Extracellular vesicles (EVs) are crucial players in the early stages of such diseases, acting as carriers of pathogens and contributing
arxiv  

The role of natural killer cells in curbing neuroinflammation [PDF]

, 2007
Benjamin M. Segal
openalex   +1 more source

Clinical Insights Into Nabais Sá‐De Vries Syndrome due to a Novel SPOP Mutation: Neuromotor, Cognitive, Adaptive, Behavioral, and Neurovisual Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nabais Sá‐De Vries syndrome (NSDVS) is an extremely rare autosomal dominant disorder caused by SPOP mutations. To date, only 10 cases have been described presenting with intellectual disability, neurological signs and symptoms, and a variable association of dysmorphic features.
Jessica Galli, Erika Loi, Federica Zanardini, Giovanna Baldoni, Francesca Novara, Serena Panigada, Roberto Ciccone, Maria Rosa Cutrì, Alice Bertoletti, Lorenzo Pinelli, Elisa Fazzi   +10 more
wiley   +1 more source

Agonism of Peroxisome Proliferator Receptor-Gamma may have Therapeutic Potential for Neuroinflammation and Parkinsons Disease [PDF]

, 2007
Randy L. Hunter, Guoying Bing
openalex   +1 more source

Microglial ApoD‐induced NLRC4 inflammasome activation promotes Alzheimer's disease progression

Animal Models and Experimental Medicine, EarlyView.
We found that NLRC4 inflammasome was activated in microglia releasing IL6 and TNF‐α to impair the hippocampal neural stem cells (NSCs) self‐proliferation. ApoD contributed to activating NLRC4 inflammasome in microglia. Targeting the ApoD provides beneficial effects on NSCs self‐proliferation and mature neurons survival.
Yaliang Yu, Jianzhou Lv, Dan Ma, Ya Han, Yaheng Zhang, Shanlong Wang, Zhitao Wang   +6 more
wiley   +1 more source

Improving criteria for dissemination in space in multiple sclerosis by including additional regions

Annals of Clinical and Translational Neurology
Objective We investigated the effects of adding regions to current dissemination in space (DIS) criteria for multiple sclerosis (MS). Methods Participants underwent brain, optic nerve, and spinal cord MRI.
Michael A. Foster, Giuseppe Pontillo, Indran Davagnanam, Sara Collorone, Ferran Prados, Baris Kanber, Marios C. Yiannakas, Lola Ogunbowale, Ailbhe Burke, Claudia A. M. Gandini Wheeler‐Kingshott, Olga Ciccarelli, Wallace Brownlee, Frederik Barkhof, Ahmed T. Toosy   +13 more
doaj   +1 more source

Progressive Increase in Infarct Size, Neuroinflammation, and Cognitive Deficits in the Presence of High Levels of Amyloid [PDF]

, 2007
Shawn N. Whitehead, Guanliang Cheng, Vladimir Hachinski, David F. Cechetto   +3 more
openalex   +1 more source

Fevogrit, a polyherbal medicine, mitigates endotoxin (lipopolysaccharide)‐induced fever in Wistar rats by regulating pro‐inflammatory cytokine levels

Animal Models and Experimental Medicine, EarlyView.
Fevogrit, an Ayurvedic medicine indicated for the management of fever, was evaluated for its pharmacological effects in rat model of endotoxin (lipopolysaccharide)‐induced high body temperature. Ultra‐high‐performance liquid chromatography analysis revealed the presence of bioactive phytometabolites in Fevogrit.
Acharya Balkrishna, Sonam Sharma, Vivek Gohel, Rani Singh, Meenu Tomer, Rishabh Dev, Sandeep Sinha, Anurag Varshney   +7 more
wiley   +1 more source