Results 171 to 180 of about 212,554 (299)

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Editorial: Neuroinflammation, neurodegeneration, and auditory-vestibular disorders. [PDF]

Front Neurol
Di Stadio A, Ralli M, Kaski D.
europepmc   +1 more source

Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx

Lin Liu (74495), Linxiao Wang (16962265), Yanjun Wang (533587), Heping Zhao (671708), Xi Gao (369965), Wen Yin (460575), Jiangang Xie (11757668)   +6 more
openalex   +1 more source

Quetiapine Attenuates the Neuroinflammation and Executive Function Deficit in Streptozotocin-Induced Diabetic Mice [PDF]

, 2019
Kexin Wang, Feng Song, Hongxing Wang, Junhui Wang, Yu Sun   +4 more
openalex   +1 more source

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

Cell, 2016
T. Sampson, Justine W. Debelius, Taren M. Thron, Stefan Janssen, Gauri G. Shastri, Z. Ilhan, Collin Challis, Catherine E. Schretter, S. Rocha, V. Gradinaru, M. Chesselet, A. Keshavarzian, K. Shannon, R. Krajmalnik-Brown, P. Wittung-Stafshede, R. Knight, S. Mazmanian   +16 more
semanticscholar   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
ABSTRACT The blood‐brain barrier (BBB) renders the delivery of nanomedicine in the brain ineffective and the detection of circulating disease‐related DNA from the brain unreliable. Here, we demonstrate that microbubble‐enhanced focused ultrasound (MB‐FUS) mediated BBB opening, supported by large‐data models predict sonication regimens for safe and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

RETRACTED: Muhammad et al. Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling. <i>Nutrients</i> 2019, <i>11</i>, 648. [PDF]

Nutrients
Muhammad T, Ikram M, Ullah R, Rehman SU, Kim MO.   +4 more
europepmc   +1 more source

Alleviation of Depression-Like Symptoms Through Orientin-MediatedRegulation of Neuroinflammation and PI3K/AKT Signaling

Yaya Du (17980544), Jingcheng Yang (671953), Fei Li (143236), Linxi Wang (3068649), Yiyuan Tian (21620670), Le Yang (345935), Lanxin Luo (5868185)   +6 more
openalex   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Bibliometric analysis and core target identification of network pharmacology on neuroinflammation in central nervous system disorders: Trends, collaborations, and future directions. [PDF]

Neuroprotection
Zhang Y, Hou S, Li J, Wang W, Jia S, Wang X, Xia Y, Wang Y.   +7 more
europepmc   +1 more source