Results 181 to 190 of about 135,205 (333)

The complement cascade: Yin–Yang in neuroinflammation – neuro‐protection and ‐degeneration [PDF]

open access: bronze, 2008
Jessy J. Alexander   +4 more
openalex   +1 more source

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei   +4 more
wiley   +1 more source

Effects of Dictyophora polysaccharide on cerebellar Purkinje cell degeneration in a chronic alcohol mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang   +5 more
wiley   +1 more source

Punica granatum peel supplementation attenuates cognitive deficits and brain injury in rat by targeting the Nrf2‐HO‐1 pathway

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 168-180, January 2023., 2023
The hydro‐ethanolic extract of P. granatum peel was standardized. ;The extract increased superoxide dismutase activity and thiol content, while reduced function of AchE and peroxidation of lipid in the scopolamine‐injured rat’s brain. ;P. granatum may attenuate scopolamine injury through targeting nuclear factor‐E2‐related factor 2 pathway ; Abstract ...
Mahsan Akbarian   +5 more
wiley   +1 more source

Modeling Sporadic Progressive Supranuclear Palsy in 3D Midbrain Organoids: Recapitulating Disease Features for In Vitro Diagnosis and Drug Discovery

open access: yesAnnals of Neurology, EarlyView.
Objective Progressive Supranuclear Palsy (PSP) is a severe neurodegenerative disease characterized by tangles of hyperphosphorylated tau protein and tufted astrocytes. Developing treatments for PSP is challenging due to the lack of disease models reproducing its key pathological features.
Elvira Immacolata Parrotta   +15 more
wiley   +1 more source

Beneficial effects of arthrocen on neuroinflammation and behavior like depression in stroke in a murine model

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 527-534, January 2023., 2023
Following oral administration of arthrocen supplement in post‐stroke depression model, the study recommended a novel protective effect by arthrocen on neuroinflammation due to stroke. It may play an antidepressant role through anti‐inflammatory as well as improved activity and mobility in mice‐induced stroke.
Ramin Goudarzi   +5 more
wiley   +1 more source

Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier [PDF]

open access: green, 2008
Mohammed F. Shamji   +7 more
openalex   +1 more source

Signs of Cortical Inflammation in Migraine Measured with Quantitative Magnetic Resonance Imaging: A Registry for Migraine (REFORM) Study

open access: yesAnnals of Neurology, EarlyView.
Objective The involvement of cortical inflammation in migraine, particularly migraine with aura, has been a subject of considerable interest, but has proved challenging to demonstrate. We aimed to detect and characterize signs of cortical inflammation in adults with migraine using a novel, multimodal magnetic resonance imaging (MRI) technique.
Rune H. Christensen   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy