Results 181 to 190 of about 212,554 (299)

Ependymal cells undergo astrocyte‐like reactivity in response to neuroinflammation [PDF]

Adam M.R. Groh, Nina Caporicci‐Dinucci, Elia Afanasiev, Maxime Bigotte, Brianna Lu, Joshua Gertsvolf, Matthew D. Smith, Thomas Garton, Liam Callahan‐Martin, Alexis Allot, Dale J. Hatrock, Victoria Mamane, Sienna Drake, Huilin Tai, Jun Ding, Alyson E. Fournier, Catherine Larochelle, Peter A. Calabresi, Jo Anne Stratton   +18 more
openalex   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Neuroinflammation demonstrated by ¹¹C-ER176 PET with amyloid and tau pathology. [PDF]

Alzheimers Dement
Kandimalla M, Lim S, Jacobson DN, Lee J, Min PH, Nycklemoe ME, Lee SB, Lundt ES, Botha H, Graff-Radford J, Jones DT, Cogswell PM, Vemuri P, Kantarci K, Knopman DS, Jack CR, Petersen RC, Lowe VJ.   +17 more
europepmc   +1 more source

Development of a novel HDAC6 PET imaging agent uncovers associations between HDAC6 overexpression and neuroinflammation in depression

Yanting Zhou, Yujia He, Xiao Zhong, Hongyan Li, Jingyi Yang, Hui Meng, Weiyao Xie, Pan Yao, Xiaoai Wu, Huawei Cai, Lin Li, Changning Wang, Wei Zhang, Ping Bai   +13 more
openalex   +1 more source

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Microglia, Astrocytes, and Oligodendrocytes in Parkinson's Disease: Neuroinflammatory Crosstalk and Emerging Therapeutic Strategies. [PDF]

Biomolecules
Kędzia D, Galita G, Majsterek I, Rozpędek-Kamińska W.   +3 more
europepmc   +1 more source

Apelin-13 ameliorates hypoxic-ischemic brain damage and improves neurological function in neonatal rats by attenuating neuroinflammation via AMPK activation

Chenxu Miao, Yue Li, Chi Qin, Chenxi Guo, Jinze Yang, Rui Mu, Meiying Cheng, Bohao Zhang, Penghua Zhang, Xin Zhao, Xiaoan Zhang   +10 more
openalex   +1 more source

Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis

, 2020
Shengnan Zhao, Zhijie Zhang, Danfeng Xu, Yanfei Wang, Ling Li   +4 more
openalex   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Antimicrobial proteins regulating neuroinflammation. [PDF]

Ann Med
Bhusal A, Lee WH, Suk K.
europepmc   +1 more source