CMPK2 promotes microglial activation through the cGAS-STING pathway in the neuroinflammatory mechanism. [PDF]
Gao F, Zheng Z, Liu X, Li J.
europepmc +1 more source
Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation [PDF]
Katie Moisse+4 more
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Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund+6 more
wiley +1 more source
Main Points Microglia become rapidly reactive in temporal lobe epilepsy (TLE). Microglia are major producers of TNFα during status epilepticus, which impairs astrocyte coupling and promotes gliosis. Depletion of microglia attenuates acute seizure activity in TLE.
Lukas Henning+10 more
wiley +1 more source
Correction: Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axis. [PDF]
Liu X+11 more
europepmc +1 more source
Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress [PDF]
Nathan L. Sparkman, Rodney W. Johnson
openalex +1 more source
Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa+11 more
wiley +1 more source
Microglia efferocytosis: an emerging mechanism for the resolution of neuroinflammation in Alzheimer's disease. [PDF]
Chen Y+6 more
europepmc +1 more source
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism [PDF]
Alexander Semmler+9 more
openalex +1 more source