Results 221 to 230 of about 252,991 (337)

cGAS-STING signaling in brain aging and neurodegeneration: molecular links and therapeutic perspectives. [PDF]

J Neuroinflammation
Li H, Cai R, Zhou Y, Jiang Y, Tan S.
europepmc   +1 more source

Immune system markers of neuroinflammation in patients with clinical diagnose of neuromyelitis optica [PDF]

, 2008
Soniza Vieira Alves‐Leon, Maria Lúcia Vellutini Pimentel, Gabrielle Sant'Anna, Fabíola Rachid Malfetano, Cláudio Duque Estrada, Thereza Quirico- Santos   +5 more
openalex   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Gut microbiota dysbiosis induces neuroinflammation in major depressive disorders: mechanisms targeting the gut-brain axis. [PDF]

Front Psychiatry
Li J, Wan B, Zhou L, Qian X, Wang F, Gu S, Ma X, Huang JH.   +7 more
europepmc   +1 more source

Differential Treatment Response, Neuroinflammation, and Psychosis Associated with Chromosome Deletion [PDF]

, 2008
Eric Hollander
openalex   +1 more source

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning, Jie Wang, Yihui Zhang, Hongrui Li, Zenan Jiang, Xinyu Su, Xiao Yang, Xiaoxuan Wu, Bing Wei, Jianmin Ying, Jian Yan, Wenbin Li   +11 more
wiley   +1 more source

Delayed Neuroinflammation Mimicking Stroke After Flow-Diverting Stent Placement: A Case Report on Diagnostic and Therapeutic Challenges. [PDF]

Cureus
Ghous MA, Chaudhry FB, Abuelgasim Malik AM, Horton G.   +3 more
europepmc   +1 more source

Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study [PDF]

, 2009
Janine Doorduin, Erik F. J. de Vries, Antoon T. M. Willemsen, Jan Cees de Groot, Rudi Dierckx, Hans Klein   +5 more
openalex   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

Implicating neuroinflammation in hippocampus, prefrontal cortex and amygdala with cognitive deficit: a narrative review. [PDF]

3 Biotech
Blossom V, Ullal SD, D'Souza MM, Ranade AV, Kumar NA, Rai R.   +5 more
europepmc   +1 more source