Results 91 to 100 of about 3,345,719 (364)

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. [PDF]

, 2015
BACKGROUND: Moderate vitamin B-12 deficiency is relatively common in older people. However, there is little robust evidence on the effect of vitamin B-12 supplementation on neurologic and cognitive outcomes in later life.
Alan D Dangour, Astrid E Fletcher, Balk, Carmel, Chou, Clarke, Cox, Dangour, de Jager, Delis, Diana Elbourne, Elizabeth Allen, Eussen, Fine, Fine, Folstein, Ford, Goldberg, Goodglass, Hin, Hunt, Institute of Medicine, Jernerén, Ken Whyte, Kerry Mills, Kimura, Leishear, Leishear, Lindenbaum, Louise Letley, Mann, Marcus Richards, Mills, Mills, O'Leary, Podsiadlo, Ricardo Uauy, Robert Clarke, Smith, Stabler, Sucharita, Sucharita, Tombaugh, Tombaugh, Turgut, Vellas, Watanabe, Yetley   +47 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Teleneurology clinics for polyneuropathy: a pilot study. [PDF]

, 2020
INTRODUCTION:Polyneuropathy (PN) is a common condition with significant morbidity. We developed tele-polyneuropathy (tele-PN) clinics to improve access to neurology and increase guideline-concordant PN care.
Cheng, Eric M, Hanssen, Andrea, Inkelas, Moira, Jamal, Nasheed I, Ong, Michael K, Saliba, Debra, Torres, Jorge A, Wilson, Andrew M   +7 more
core  

Assessment of acute headache in adults - what the general physician needs to know. [PDF]

, 2018
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal, Cappelen-Smith, Dodick, Hoffmann, Mac Grory, Macdonald, omi, Savitz, Sheikh, Solomon   +9 more
core   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Familial multiple cavernous malformation syndrome : MR features in this uncommon but silent threat [PDF]

, 2016
Cerebral cavernous malformations (CCM) are vascular malformations in the brain and spinal cord. The familial form of cerebral cavernous malformation (FCCM) is uncommon.
Lemmerling, Marc, Mespreuve, Marc, Vanhoenacker, Filip   +2 more
core   +3 more sources

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Unconventional Biomarkers in Dementia Trough Neurological Examination: A Literature Review

Iatreia
Introduction: Blood and cerebrospinal fluid biomarkers have gained prominence in dementia diagnosis; however, they are not always available. Objectives: To describe unconventional biomarkers identifiable during neurological examination.
Salazar-Londoño, Salomón, Pérez-Foucrier, Valeria, Tengonó-Guarín, María José, Franky-Escobar, Isabella, Iragorri, Angela   +4 more
doaj   +1 more source

Expert-level detection of acute intracranial hemorrhage on head computed tomography using deep learning. [PDF]

, 2019
Computed tomography (CT) of the head is used worldwide to diagnose neurologic emergencies. However, expertise is required to interpret these scans, and even highly trained experts may miss subtle life-threatening findings. For head CT, a unique challenge
Hӓne, Christian, Kuo, Weicheng, Malik, Jitendra, Mukherjee, Pratik, Yuh, Esther L   +4 more
core