Results 51 to 60 of about 3,345,719 (364)

Diagnostic Inaccuracies in Children with “First Seizure”

Pediatric Neurology Briefs, 2007
A prospective cohort study of 127 children aged 1 month through 17 years seen in the First Seizure clinic at the Alberta Children's Hospital between Jan 1, 2004 and August 30, 2005 determined the range of diagnoses and the prevalence of previous ...
J Gordon Millichap
doaj   +1 more source

Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?

Arquivos de Neuro-Psiquiatria, 2001
Coronary artery bypass surgery (CABG) without cardiopulmonary bypass (CPB) may potentially reduce the number of microembolic signals (MES) associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome ...
Suzana M. F. Malheiros, Ayrton R. Massaro, Alberto A. Gabbai, Clodualdo J. N. Pessa, Luis R. Gerola, João N. R. Branco, Edgar B. Lira Filho, Dejaldo M. J. Christofalo, Darwin Federico, Antonio C. Carvalho, Enio Buffolo   +10 more
doaj   +3 more sources

Is Brain MRI Essential for the Evaluation of Headache in Patients with Normal Neurological Examination?

Genel Tıp Dergisi, 2022
Aim: Headache is amongst the most common reasons of consulting a doctor. In addition to impairing the quality of life of the individual, there are societal as well as fiscal outcomes like workforce loss along with health expenditures.
Dilara Patat, Fatih Çankal
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Feasibility for evaluating motor aspects of Parkinson's disease through video consultations in a resource-limited setting in Southern Brazil

Arquivos de Neuro-Psiquiatria, 2023
Background Performing motor evaluations using videoconferencing for patients with Parkinson's disease (PD) is safe and feasible. However, the feasibility of these evaluations is not adequately studied in resource-limited settings. Objective To
Daniel Teixeira-dos-Santos, Daniel Monte Freire Camelo, Matheus Zschornack Strelow, Maysa Tayane Santos Silva, Paula Führ, Letícia Winer Marins, Artur Francisco Schumacher Schuh   +6 more
doaj   +1 more source

Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases [PDF]

, 2014
Retrospective study of dogs with TBI that underwent 1.5T MRI within 14 days after head trauma. MRI evaluators were blinded to the clinical presentation, and all images were scored based on an MRI grading system (Grade I [normal brain parenchyma] to Grade
Asikainen, Bazarian, Bigler, Brain Trauma Foundation, Byrne, Chew, Englander, Firsching, Frey, Friedenberg, Hicks, Hilario, Kearsley-Fleet, Klein, Kornegay, Lagares, Lannsjö, Lee, Lowenstein, Löscher, Management of Concussion/mTBI Working Group, McDonald, Mittl, Orrison, Pearl, Platt, Sande, Schwartz-Porsche, Shenton, Shores, Simpson, Skandsen, Steinmetz, Tanoue, Vespa, Wendt-Hornickle, Wilde, Yuh, Zuercher   +38 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A Study of Cerebral Performance Categories Based on Initial Rhythm and Resuscitation Time Following In-Hospital Cardiac Arrest in a State Hospital in Turkey [PDF]

Hospital Practices and Research, 2018
Background: The cerebral performance category (CPC) score is widely used in research and quality assurance to assess neurologic outcome following cardiac arrest. However, little is known about the results of the CPC in Turkey. Objective: This study aimed
Faruk Cicekci, Ali Ulvi Uca, Inci Kara, Iskender Kara   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source