Results 101 to 110 of about 227,565 (303)

The Effect of Repetitive Transcranial Magnetic Stimulation on Motor Symptoms in Hereditary Spastic Paraplegia

Neural Plasticity, 2019
Background. Hereditary spastic paraplegia (HSP) is a heterogeneous group of inherited disorders affecting predominantly the motor cortex and pyramidal tract, which results in slowly progressing gait disorders, as well as spasticity and weakness of lower ...
J. Antczak, J. Pera, M. Dąbroś, W. Koźmiński, M. Czyżycki, K. Wężyk, M. Dwojak, M. Banach, A. Slowik   +8 more
doaj   +1 more source

Neural correlates of gait disorders in neurological conditions

, 2016
Among the oldest old, around 20 % still walk normally, suggesting that gait disorders are not an unavoidable consequence of aging. Intense researches involving clinicians and neuroscientists are focusing on the neural mechanisms of gait control, in order to understand the pathophysiology of gait disorders affecting neurological conditions.
openaire   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

EXPLOITING VISUAL CUES FOR LEARNING GAIT PATTERNS ASSOCIATED WITH NEUROLOGICAL DISORDERS

Jurnal Teknologi, 2017
Records of cases involving neurological disorders often exhibit abnormalities in the gait pattern of an individual. As mentioned in various articles, the causes of various gait disorders can be attributed to neurological disorders. Hence analysis of gait abnormalities can be a key to predict the type of neurological disorders as a part of early ...
Kuhelee Roy, Geelapaturu Subrahmanya Venkata Radha Krish Rao, Savarimuthu, Margret Anouncia   +2 more
openaire   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Enhancing therapeutic decisions during robot-assisted gait therapy: current challenges and development of a novel app-based therapy protocol to address them

BMC Medical Informatics and Decision Making
Background Therapists’ decisions on influencing patient behavior during robot-assisted gait therapy directly impact clinical practice and, thus, therapeutic efficacy.
Florian van Dellen, Tabea Aurich, Rob Labruyère   +2 more
doaj   +1 more source

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source

Feasibility and clinical integration study on low⁃cost digital gait analysis system based on dual Kinect V2

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To develop a low⁃cost digit⁃intelligent gait analysis system based on dual Kinect V2 sensors and universal open⁃source software platforms (DKS), and to evaluate its feasibility and accuracy for gait analysis. Methods A total of 15 patients with
ZHANG Shi⁃yu, CHEN Guo⁃rong, MAIMAITIABULA Saimaiti, XU Xing⁃hua, ZHUANG Jia⁃shu, CHEN Xiao⁃lei   +5 more
doaj   +1 more source