Results 131 to 140 of about 10,652,159 (339)

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Neurological Manifestations of Coronavirus Disease 2019 in Hospitalized Patients: A Lebanese Cohort Study [PDF]

, 2023
Taghrid El Hajj, Mahmoud Hassoun, Ranime Harb, Oriana Tarabay, Amine Zarzour, Maya Zeineddine   +5 more
openalex   +1 more source

Functional motor disorders associated with other neurological diseases: Beyond the boundaries of “organic” neurology

European Journal of Neurology, 2020
The aims of this study were to describe the clinical manifestations of functional motor disorders (FMDs) coexisting with other neurological diseases (“comorbid FMDs”), and to compare comorbid FMDs with FMDs not overlapping with other neurological ...
M. Tinazzi, C. Geroin, R. Erro, Enrico Marcuzzo, S. Cuoco, R. Ceravolo, S. Mazzucchi, A. Pilotto, A. Padovani, Luigi Michele Romito, R. Eleopra, M. Zappia, A. Nicoletti, C. Dallocchio, C. Arbasino, F. Bono, A. Pascarella, B. Demartini, O. Gambini, N. Modugno, Enrica Olivola, L. Bonanni, E. Antelmi, E. Zanolin, A. Albanese, G. Ferrazzano, R. de Micco, L. Lopiano, G. Calandra-Buonaura, M. Petracca, M. Esposito, A. Pisani, P. Manganotti, F. Stocchi, M. Coletti Moja, A. Antonini, Tommaso Ercoli, F. Morgante   +37 more
semanticscholar   +1 more source

Brain Age from the Electroencephalogram of Sleep [PDF]

, 2018
The human electroencephalogram (EEG) of sleep undergoes profound changes with age. These changes can be conceptualized as "brain age", which can be compared to an age norm to reflect the deviation from normal aging process.
Akeju, Oluwaseun, Bianchi, Matt T., Carvalho, Diego Z., Cash, Sydney S., Goparaju, Balaji, Oliva, Jefferson T., Paixao, Luis, Sun, Haoqi, Thomas, Robert Joseph, van Leeuwen, Kicky G., Westover, M. Brandon   +10 more
core   +3 more sources

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source

Ticagrelor versus clopidogrel in CYP2C19 loss-of-function carriers with stroke or TIA stratified by age and renal function: CHANCE-2 trial substudy

Renal Failure
Objective To compare the efficacy and safety of ticagrelor versus clopidogrel in stroke patients who were CYP2C19 loss-of-function (LOF) carriers stratified by age and renal function.Methods Patients in the CHANCE-2 trial were randomized to ticagrelor ...
Yu Wu, Yilun Zhou, Yuesong Pan, Aoming Jin, Xia Meng, Hao Li, Yilong Wang, Yong Jiang, Yongjun Wang   +8 more
doaj   +1 more source

Editorial: Innovative OMICs-technology applications to reach a diagnosis and bring new therapies to immune-mediated neurological diseases [PDF]

, 2023
Laura Otero‐Ortega, Mireya Fernández-Fournier, Haritz Irizar, David Otaegui, Exuperio Díez‐Tejedor   +4 more
openalex   +1 more source

Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi, Samantha N. Roman, Mohammad S. Sadaghiani, Lilja B. Solnes, Scott D. Newsome   +4 more
wiley   +1 more source

Function and therapeutic value of astrocytes in neurological diseases

Nature reviews. Drug discovery, 2022
Hong-Gyun Lee, Michael A. Wheeler, F. Quintana   +2 more
semanticscholar   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source