Results 51 to 60 of about 685,470 (326)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The comparison of general movements assessment and neurological examination during early infancy

open access: yesThe Turkish Journal of Pediatrics, 2016
This prospective single-blinded study was performed to evaluate general movements (GMs) in group of high-risk, low-birth-weight and preterm infants and to compare results with neurologic examination.
Büşra Kepenek-Varol   +5 more
doaj   +1 more source

Reasons for Diagnostic Delay of Foot Drop Caused by Parasagittal Meningioma: Two Case Reports

open access: yesCase Reports in Neurology, 2021
Foot drop is defined as an impaired ability or inability of dorsiflexion. Peripheral nervous system injuries are commonly considered as the cause of this condition. The central causes including parasagittal meningioma are also described in the literature
Duc Thuan Nguyen   +4 more
doaj   +1 more source

Extended Timed Up and Go assessment as a clinical indicator of cognitive state in Parkinson\u27s disease [PDF]

open access: yes, 2017
Objective: To evaluate a modified extended Timed Up and Go (extended-TUG) assessment against a panel of validated clinical assessments, as an indicator of Parkinson’s disease (PD) severity and cognitive impairment. Methods: Eighty-seven participants with
Anderton, R   +7 more
core   +2 more sources

Early motor trajectories predict motor but not cognitive function in preterm- and term-born adults without pre-existing neurological conditions [PDF]

open access: yes, 2020
Very preterm (VP; 0.05). Motor problems in childhood were homotypically associated with poorer motor competence in adulthood. Similarly, early cognitive problems were homotypically associated with adult cognitive outcomes. Thus, both motor and cognitive
Bartmann, Peter   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PENGARUH KADAR GLUKOSA DARAH SEWAKTU TERHADAP KELUARAN NEUROLOGIK PADA PENDERITA STROKE ISKEMIK FASE AKUT NONDIABETIK [PDF]

open access: yes, 2011
Background : An increasing of blood glucose levels is presumed to aggravate the neurological outcome of ischemic stroke patients. The research about association between increased blood glucose levels on nondiabetic patients with ischemic stroke and the ...
Napitupulu, Edward Yando
core  

Neurological Examination and Anatomy [PDF]

open access: gold, 2023
Meredyth L. Jones, Matt D. Miesner
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Considerações sobre o reflexo tônico cervical de Magnus: De Kleijn Considerations about the Magnus: De Kleijn tonic neck reflex

open access: yesArquivos de Neuro-Psiquiatria, 1997
O reflexo tônico cervical de Magnus - De Kleijn é analisado levando-se em conta as psicologias do desenvolvimento de Gesell, Spitz e Piaget. É considerada sua natureza filogenética, realçado o significado favorável de seu desaparecimento em torno do ...
Paulo Bearzoti
doaj   +1 more source

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