Results 141 to 150 of about 1,882,529 (345)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Neurological manifestations of COVID-19

, 2020
Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has turned out to be a formidable pandemic. Upcoming evidence from confirmed cases of COVID-19 suggests an anticipated incursion of patients with ...
Baig, Abdul Mannan, Kanwar, Dureshahwar, Wasay, Mohammad   +2 more
core  

Neurological manifestations of primary Sjögren’s syndrome

, 2018
Primary Sjögren’s syndrome (pSS) is an autoimmune connective tissue disease affecting the exocrine glands, leading to damage of their structure and impairment of their function.
Joanna Perzyńska-Mazan, Maria Maślińska, Robert Gasik   +2 more
core   +1 more source

Potential neurological manifestations of COVID-19: a narrative review

, 2022
Neurological manifestations are increasingly reported in a subset of COVID-19 patients. Previous infections related to coronaviruses, namely Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome (MERS) also appeared to have ...
Christo, Paul J, Pergolizzi, Joseph V, Giustino Varrassi, Varrassi, G, Pergolizzi, Joseph V., Jr.,, Breve, Frank,, Paul J. Christo, Magnusson, Peter,, Joseph V. Pergolizzi, Taylor, R, Paladini, A, Wollmuth, C, Maninder Chopra, Varrassi, Giustino,, Varrassi, Giustino, Antonella Paladini, Nalamasu, Rohit,, Raffa, Robert B.,, Rohit Nalamasu, Nalamasu, Rohit, Taylor, Robert,, Wollmuth, Charles,, LeQuang, Jo Ann, Raffa, RB, Charles Wollmuth, LeQuang, Jo Ann,, Breve, Frank, Wollmuth, Charles, Pergolizzi, JVJ, LeQuang, JA, Paladini, Antonella,, Robert B. Raffa, Paladini, Antonella, Chopra, M, Jo Ann LeQuang, Christo, Paul J.,, Frank Breve, Peter Magnusson, Breve, F, Robert Taylor, Chopra, Maninder,, Magnusson, Peter, Magnusson, P,, Taylor, Robert, Raffa, Robert B, Chopra, Maninder   +45 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Clinical manifestations of human brucellosis : a systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: The objectives of this systematic review, commissioned by WHO, were to assess the frequency and severity of clinical manifestations of human brucellosis, in view of specifying a disability weight for a DALY calculation.
Schelling, E., Esther Schelling, Lisa Crump (113919), Jakob Zinsstag (113928), Jan Hattendorf (113923), Helena Greter (113921), Esther Schelling (113925), Dean, A. S., Hattendorf, J., Greter, H., Lisa Crump, Crump, L., Helena Greter, Jakob Zinsstag, Anna S. Dean (113917), Anna S Dean, Zinsstag, J., Jan Hattendorf   +17 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

COVID-19 Neurological Manifestations

International Clinical Neuroscience Journal, 2020
Arash Azhideh
doaj   +1 more source

Neurologic Manifestations of AIDS

Medicine, 1987
An understanding of the biologic characteristics and cellular tropism of human immunodeficiency virus (HIV) is critical to appreciate the diverse neurologic manifestations of HIV infection in patients with the acquired immunodeficiency syndrome (AIDS).
openaire   +2 more sources

Neurological manifestations of Behcet s disease

Saudi Medical Journal, 2006
To determine the prevalence, clinical manifestations, and laboratory features of Neuro-Behcet`s disease.This prospective study was carried out in the Behcet`s Research Clinic in Shiraz (south-west Iran) and included the patients referred from 1990-1999.
Afshin, Borhani-Haghighi, Shahdokht, Samangooie, Nahid, Ashjazadeh, Alireza, Nikseresht, Abdolhamid, Shariat, Gholamali, Yousefipour, Anahid, Safari   +6 more
openaire   +3 more sources