Results 121 to 130 of about 996,320 (184)
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
A Tribute to a Gentle Giant (Fondly Called CHIEF). [PDF]
Ann Indian Acad NeurolUmaiorubahan M.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer +10 more
wiley +1 more source
Author Correction: Caprini score combined with thrombotic molecular markers for predicting DVT in patients with traumatic fractures. [PDF]
Sci RepWu Z, Du Y, Cai X, Xu Q.
europepmc +1 more source
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
Advanced Healthcare Materials, EarlyView.SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini +12 more
wiley +1 more source
Secondary progression activity monitoring in MS despite an early highly active treatment the SPAM study. [PDF]
Eur J NeurolCohen M +43 more
europepmc +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Correction: Antiseizure Medications and Sudden Unexpected Death in Epilepsy: An Updated Review. [PDF]
CNS DrugsBosch AT, Sander JW, Thijs RD.
europepmc +1 more source
Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions
Advanced Materials, EarlyView.Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng +6 more
wiley +1 more source