Results 41 to 50 of about 1,656,609 (285)
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
The diagnostic value of the neurological examination in coma of unknown etiology [PDF]
, 2021 W. U. Schmidt +3 more
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
What's happening in Neurology® Neuroimmunology & Neuroinflammation
Neurology, 2018 Articles appearing in the January 2018 ...
semanticscholar +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
FEBS Open Bio, EarlyView.Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Intravenous Thrombolysis after Reversal of Dabigatran by Idarucizumab: A Case Report
Case Reports in Neurology, 2016 We describe a 75-year-old female patient with nonvalvular atrial fibrillation who presented with acute ischemic stroke during treatment with dabigatran 2 × 110 mg per day.
Waldemar Kafke +2 more
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Sex Differences in Academic Rank and Publication Rate at Top-Ranked US Neurology Programs
JAMA Neurology, 2018 Importance Women are underrepresented in academic neurology, and the reasons for the underrepresentation are unclear. Objective To explore potential sex differences in top-ranked academic neurology programs by comparing the number of men and women at ...
M. McDermott +6 more
semanticscholar +1 more source
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source