Exploratory Design of a Hands-free Video Game Controller for a Quadriplegic Individual [PDF]
From colored pixels to hyper-realistic 3D landscapes of virtual reality, video games have evolved immensely over the last few decades. However, video game input still requires two-handed dexterous finger manipulations for simultaneous joystick and trigger or mouse and keyboard presses.
arxiv +1 more source
Diseases of the neuromuscular junction
The neuromuscular junction is a prototype synapse and it is also the site of well-characterised autoimmune and hereditary disorders. In the presynaptic terminal, voltage-gated potassium channels and voltage-gated calcium channels are subtly altered in genetic disorders and mutations in the enzyme that synthesises acetylcholine have been demonstrated in
McConville, J, Vincent, A
openaire +4 more sources
Molecular confirmation of Sarcocystis fayeri in a donkey [PDF]
Sarcocystis fayeri is a canine protozoan parasite with an equine intermediate host. Historically classified as an incidental pathogen, recent literature has described the toxic effects of Sarcocystis fayeri in human food poisoning, and highlighted ...
Coultous, Robert M.+4 more
core +1 more source
Morphological characteristics of motor neurons do not determine their relative susceptibility to degeneration in a mouse model of severe spinal muscular atrophy [PDF]
Spinal muscular atrophy (SMA) is a leading genetic cause of infant mortality, resulting primarily from the degeneration and loss of lower motor neurons.
A Lionikas+48 more
core +2 more sources
Daratumumab–bortezomib–dexamethasone use in relapsed POEMS syndrome
POEMS syndrome is a rareparaneoplastic disorder driven by an underlying low level plasma cell dyscrasiaand associated with elevated serum vascular endothelial growth factor (VEGF).
Jahanzaib Khwaja+5 more
doaj +1 more source
Brain Damage and Motor Cortex Impairment in Chronic Obstructive Pulmonary Disease: Implication of Nonrapid Eye Movement Sleep Desaturation [PDF]
Nonrapid eye movement (NREM) sleep desaturation may cause neuronal damage due to the withdrawal of cerebrovascular reactivity. The current study (1) assessed the prevalence of NREM sleep desaturation in nonhypoxemic patients with chronic obstructive pulmonary disease (COPD) and (2) compared a biological marker of cerebral lesion and neuromuscular ...
arxiv +1 more source
The Role of Contraction Mode in Determining Exercise Tolerance, Torque-Duration Relationship, and Neuromuscular Fatigue [PDF]
Purpose: Critical torque (CT) and work done above it (W') are key predictors of exercise performance associated with neuromuscular fatigue. The aim of the present study was to understand the role of the metabolic cost of exercise in determining exercise tolerance, CT and W' and the mechanisms of neuromuscular fatigue.Methods: Twelve subjects performed ...
arxiv +1 more source
Sugammadex for reversal of neuromuscular blockade: A retrospective analysis of clinical outcomes and cost-effectiveness in a single center [PDF]
OBJECTIVE: The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen for neuromuscular block (NMB) management.
BARATTO, FABIO+3 more
core +1 more source
Rate of complications due to neuromuscular scoliosis spine surgery in a 30-years consecutive series [PDF]
PURPOSE: The aim of this study was to evaluate the rate of intraoperative and postoperative complications in a large series of patients affected by neuromuscular scoliosis. METHODS: It was a monocentric retrospective study.
CALDERARO, COSMA+5 more
core +1 more source
Anthropometry of arm: nutritional risk indicator in amyotrophic lateral sclerosis
The aim of the paper is to examine the correlation between clinical data, nutritional, respiratory and functional parameters in amyotrophic lateral sclerosis (ALS). This is a descriptive study of 111 ALS patients [91 spinal onset (GS) and 20 bulbar onset
Cristina Cleide dos Santos Salvioni+3 more
doaj +1 more source