Daratumumab–bortezomib–dexamethasone use in relapsed POEMS syndrome
eJHaem, 2022 POEMS syndrome is a rareparaneoplastic disorder driven by an underlying low level plasma cell dyscrasiaand associated with elevated serum vascular endothelial growth factor (VEGF).
Jahanzaib Khwaja +5 more
doaj +1 more source
Anthropometry of arm: nutritional risk indicator in amyotrophic lateral sclerosis
Neurology International, 2015 The aim of the paper is to examine the correlation between clinical data, nutritional, respiratory and functional parameters in amyotrophic lateral sclerosis (ALS). This is a descriptive study of 111 ALS patients [91 spinal onset (GS) and 20 bulbar onset
Cristina Cleide dos Santos Salvioni +3 more
doaj +1 more source
Genetic neuromuscular disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2002 The clinical practice of neuromuscular disease is currently undergoing enormous change as a direct result of the wealth of recent molecular genetic discoveries. Indeed, the majority of gene discoveries in the area of neurological disease relate to neuromuscular disorders.
Michael G. Hanna, Mary M. Reilly
openaire +3 more sources
A Splicing Mutation in the Novel Mitochondrial Protein DNAJC11 Causes Motor Neuron Pathology Associated with Cristae Disorganization, and Lymphoid Abnormalities in Mice [PDF]
, 2014 Mitochondrial structure and function is emerging as a major contributor to neuromuscular disease, highlighting the need for the complete elucidation of the underlying molecular and pathophysiological mechanisms. Following a forward genetics approach with
Douni, E +9 more
core +1 more source
BMC Molecular and Cell Biology, 2020 Background Popeye domain-containing proteins 1 and 2 (POPDC1 and POPDC2) are transmembrane proteins involved in cyclic AMP-mediated signalling processes and are required for normal cardiac pacemaking and conduction.
Ian Holt +5 more
doaj +1 more source
Molecular confirmation of Sarcocystis fayeri in a donkey [PDF]
, 2017 Sarcocystis fayeri is a canine protozoan parasite with an equine intermediate host. Historically classified as an incidental pathogen, recent literature has described the toxic effects of Sarcocystis fayeri in human food poisoning, and highlighted ...
Coultous, Robert M. +4 more
core +1 more source
Rate of complications due to neuromuscular scoliosis spine surgery in a 30-years consecutive series [PDF]
, 2017 PURPOSE: The aim of this study was to evaluate the rate of intraoperative and postoperative complications in a large series of patients affected by neuromuscular scoliosis. METHODS: It was a monocentric retrospective study.
CALDERARO, COSMA +5 more
core +1 more source
Cells, 2021 Heterogeneity of glia in different CNS regions may contribute to the selective vulnerability of neuronal populations in neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS).
Rebecca San Gil +4 more
doaj +1 more source
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
, 2012 Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J +2 more
core +2 more sources
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis [PDF]
, 2010 Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo.
Bender, F.L.P. +9 more
core +4 more sources