Results 111 to 120 of about 189,433 (365)

NEUROMUSCULAR DISEASE AND ANAESTHESIA

open access: yesBritish Journal of Anaesthesia, 1974
Diseases affecting the neuromuscular system are numerous and not uncommon (for classification see Appendix). Almost all of the drugs used in anaesthesia have either a direct or an indirect effect on muscle, and so an understanding by anaesthetists of the neuromuscular diseases is essential in view of the universal requirement of muscle relaxation ...
openaire   +3 more sources

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

open access: yes, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J   +2 more
core   +2 more sources

Simulation Experiment of BCI Based on Imagined Speech EEG Decoding [PDF]

open access: yesarXiv, 2017
Brain Computer Interface (BCI) can help patients of neuromuscular diseases restore parts of the movement and communication abilities that they have lost. Most of BCIs rely on mapping brain activities to device instructions, but limited number of brain activities decides the limited abilities of BCIs. To deal with the problem of limited ablility of BCI,
arxiv  

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

open access: yesAdvanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu   +15 more
wiley   +1 more source

Retinal Dystrophies Associated with Mutations in the RP1 Gene: Genotype–Phenotype Correlations

open access: yesCurrent Issues in Molecular Biology
Background: We evaluated the genetic and phenotypic features of a cohort of 10 Italian patients affected by Retinitis Pigmentosa (RP) associated with RP1 sequence variants.
Vito Spagnuolo   +11 more
doaj   +1 more source

Accurate and Noninvasive Dysphagia Assessment via a Soft High‐Density sEMG Electrode Array Conformal to the Submental and Infrahyoid Muscles

open access: yesAdvanced Science, EarlyView.
A stretchable, breathable, large‐area high‐density sEMG (HD‐sEMG) electrode array is reported, which enables seamless integration to the complex surface of the submental and infrahyoid muscles to detect high‐fidelity HD‐sEMG signals during swallowing.
Weijie Hong   +9 more
wiley   +1 more source

A Splicing Mutation in the Novel Mitochondrial Protein DNAJC11 Causes Motor Neuron Pathology Associated with Cristae Disorganization, and Lymphoid Abnormalities in Mice [PDF]

open access: yes, 2014
Mitochondrial structure and function is emerging as a major contributor to neuromuscular disease, highlighting the need for the complete elucidation of the underlying molecular and pathophysiological mechanisms. Following a forward genetics approach with
Douni, E   +9 more
core   +1 more source

Acute Hepatic Porphyria Should Be Included in the Diagnostic Work-Up of Patients with Resistant Hypertension or Suspected Secondary Hypertension

open access: yesMedical Sciences
Secondary hypertension and resistant hypertension may result from potentially treatable acquired or hereditary diseases. Inherited Metabolic Disorders are not routinely included in the differential diagnosis of these contexts associated with hypertension,
Paulo de Lima Serrano   +11 more
doaj   +1 more source

Coexistence of Pernicious Anemia and Myasthenia Gravis—A Rare Combination of Autoimmune Diseases in Taiwan

open access: yesJournal of the Formosan Medical Association, 2006
About 5-10% of patients with myasthenia gravis concomitantly have other autoimmune diseases. However, the coexistence of myasthenia gravis and pernicious anemia is rare.
Kuo-Hsuan Chang   +4 more
doaj   +1 more source

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